Rate of Clinical Complete Response for 1 Year or More in Bone-Metastatic Breast Cancer after Comprehensive Treatments including Autologous Formalin-Fixed Tumor Vaccine

المؤلفون المشاركون

Kuranishi, Fumito
Imaoka, Yuki
Sumi, Yuusuke
Uemae, Yoji
Yasuda-Kurihara, Hiroko
Ishihara, Takeshi
Miyazaki, Tsubasa
Ohno, Tadao

المصدر

International Journal of Breast Cancer

العدد

المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-11، 11ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2018-01-22

دولة النشر

مصر

عدد الصفحات

11

التخصصات الرئيسية

الأمراض
الطب البشري

الملخص EN

Introduction.

No effective treatment has been developed for bone-metastatic breast cancer.

We found 3 cases with clinical complete response (cCR) of the bone metastasis and longer overall survival of the retrospectively examined cohort treated comprehensively including autologous formalin-fixed tumor vaccine (AFTV).

Patients and Methods.

AFTV was prepared individually for each patient from their own formalin-fixed and paraffin-embedded breast cancer tissues.

Results.

Three patients maintained cCR status of the bone metastasis for 17 months or more.

Rate of cCR for 1 year or more appeared to be 15% (3/20) after comprehensive treatments including AFTV.

The median overall survival time (60.0 months) and the 3- to 8-year survival rates after diagnosis of bone metastasis were greater than those of historical control cohorts in Japan (1988–2002) and in the nationwide population-based cohort study of Denmark (1999–2007).

Conclusion.

Bone-metastatic breast cancer may be curable after comprehensive treatments including AFTV, although larger scale clinical trial is required.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Kuranishi, Fumito& Imaoka, Yuki& Sumi, Yuusuke& Uemae, Yoji& Yasuda-Kurihara, Hiroko& Ishihara, Takeshi…[et al.]. 2018. Rate of Clinical Complete Response for 1 Year or More in Bone-Metastatic Breast Cancer after Comprehensive Treatments including Autologous Formalin-Fixed Tumor Vaccine. International Journal of Breast Cancer،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1169453

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Kuranishi, Fumito…[et al.]. Rate of Clinical Complete Response for 1 Year or More in Bone-Metastatic Breast Cancer after Comprehensive Treatments including Autologous Formalin-Fixed Tumor Vaccine. International Journal of Breast Cancer No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1169453

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Kuranishi, Fumito& Imaoka, Yuki& Sumi, Yuusuke& Uemae, Yoji& Yasuda-Kurihara, Hiroko& Ishihara, Takeshi…[et al.]. Rate of Clinical Complete Response for 1 Year or More in Bone-Metastatic Breast Cancer after Comprehensive Treatments including Autologous Formalin-Fixed Tumor Vaccine. International Journal of Breast Cancer. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1169453

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1169453