The Impact of Locoregional Therapy in Nonmetastatic Inflammatory Breast Cancer: A Population-Based Study
المؤلفون المشاركون
Wong, Jan H.
Vohra, Nasreen A.
Muzaffar, Mahvish
Johnson, Helen M.
Liles, Darla
المصدر
International Journal of Breast Cancer
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-06-03
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Inflammatory breast cancer (IBC) is a rare but most aggressive breast cancer subtype.
The impact of locoregional therapy on survival in IBC is controversial.
Methods.
Patients with nonmetastatic IBC between 1988 and 2013 were identified in the Surveillance, Epidemiology, and End Results (SEER) registry.
Results.
We identified 7,304 female patients with nonmetastatic inflammatory breast cancer (IBC) who underwent primary tumor surgery.
Most patients underwent total mastectomy with only 409 (5.6%) undergoing a partial mastectomy.
In addition, 4,559 (62.4%) were also treated with radiation therapy.
The patients who underwent mastectomy had better survival compared to partial mastectomy (49% versus 43%, p = 0.003).
The addition of radiation therapy was also associated with improved 5-year survival (55% versus 40%, p < 0.001).
Multivariate analysis showed that black race HR (1.22, 95% CI 1.18–1.35), ER negative status (HR 1.22, 95% CI 1.16–1.28), and higher grade (HR 1.14, 95% CI 1.07–1.20) were associated with poor outcome.
Cox proportional hazards model showed that total mastectomy (HR 0.75, 95% CI 0.65–0.85) and radiation (HR 0.64, 95% CI 0.61–0.69) were associated with improved survival.
Conclusions.
Optimal locoregional therapy for women with nonmetastatic IBC continues to be mastectomy and radiation therapy.
These data reinforce the prevailing treatment algorithm for nonmetastatic IBC.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Muzaffar, Mahvish& Johnson, Helen M.& Vohra, Nasreen A.& Liles, Darla& Wong, Jan H.. 2018. The Impact of Locoregional Therapy in Nonmetastatic Inflammatory Breast Cancer: A Population-Based Study. International Journal of Breast Cancer،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1169458
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Muzaffar, Mahvish…[et al.]. The Impact of Locoregional Therapy in Nonmetastatic Inflammatory Breast Cancer: A Population-Based Study. International Journal of Breast Cancer No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1169458
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Muzaffar, Mahvish& Johnson, Helen M.& Vohra, Nasreen A.& Liles, Darla& Wong, Jan H.. The Impact of Locoregional Therapy in Nonmetastatic Inflammatory Breast Cancer: A Population-Based Study. International Journal of Breast Cancer. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1169458
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1169458
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر