Sex-Specific Association between Serum 25-Hydroxyvitamin D and Metabolic Risk Factors in T2DM Patients
المؤلفون المشاركون
Sun, Xiaomin
Zhou, Sirui
He, Xin
Wang, Youfa
Cui, Wei
المصدر
International Journal of Endocrinology
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-06-04
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objective.
To evaluate the relationship between serum 25-hydroxyvitamin (25(OH)D) levels and metabolic risk factor levels in patients with type 2 diabetes mellitus (T2DM) on a sex-specific basis.
Methods.
Our study comprised 507 patients with T2DM (321 men, 186 women; median age, 59 years).
The metabolic risk factors examined included lipoprotein(a), glycated albumin (GA-L), and random blood glucose (RBG); the levels of these parameters were determined enzymatically.
Serum 25(OH)D levels were measured by commercial ELISA kits.
Participants were divided into low and high 25(OH)D groups according to the median 25(OH)D concentration (13.2 ng/mL).
Two-way analysis of covariance and multiple linear regression analysis were performed.
Results.
The median 25(OH)D concentration was 13.9 ng/mL in men and 12.2 ng/mL in women.
25(OH)D levels inversely correlated with levels of three metabolic risk factors in a sex-dependent manner after adjusting for several confounding factors.
These were lipoprotein(a) in men (141.3 ± 137.9 and 195.3 ± 204.8 mg/L in high and low 25(OH)D groups, respectively; P<0.05); GA-L in women (22.2 ± 8.8 vs.
23.3 ± 7.3% in high and low 25(OH)D groups, respectively; P<0.05).
In a subgroup analysis, serum 25(OH)D levels inversely correlated with lipoprotein(a) levels in men (β = −0.185, P=0.002) and RBG levels in women (β = −0.176, P=0.028).
Conclusion.
Higher serum 25(OH)D levels indicate a more favorable lipid profile in men and a more favorable glucose profile in women.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sun, Xiaomin& Zhou, Sirui& He, Xin& Wang, Youfa& Cui, Wei. 2020. Sex-Specific Association between Serum 25-Hydroxyvitamin D and Metabolic Risk Factors in T2DM Patients. International Journal of Endocrinology،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1170617
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sun, Xiaomin…[et al.]. Sex-Specific Association between Serum 25-Hydroxyvitamin D and Metabolic Risk Factors in T2DM Patients. International Journal of Endocrinology No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1170617
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sun, Xiaomin& Zhou, Sirui& He, Xin& Wang, Youfa& Cui, Wei. Sex-Specific Association between Serum 25-Hydroxyvitamin D and Metabolic Risk Factors in T2DM Patients. International Journal of Endocrinology. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1170617
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1170617
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر