Synthesis, Characterization, and Biological Evaluation of a New Hydrogen-Bonded Charge-Transfer Complex of 2-Amino-4-methoxy-6-methylpyrimidine
المؤلف
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-12-16
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
A new hydrogen-bonded charge-transfer (HB-CT) complex formed between the donor 2-amino-4-methoxy-6-methylpyrimidine (AMMP) and the π-acceptor 2,5-dihydroxy-p-benzoquinone (DHBQ) was investigated in both solid and solution states.
The investigation was conducted using UV-Vis, CHN, FTIR, 1H NMR, XRD, and TG-DTA analyses.
The molecular composition of the CT complex in MeOH was found to be 1 : 1.
The formation constant (KCT), molecular extinction coefficient (ε), and several other spectroscopic physical parameters were evaluated at different temperatures.
The thermodynamic properties of the CT interaction in MeOH were studied by calculating the enthalpy (ΔH°), entropy (ΔS°), and free energy (ΔG°).
The thermodynamic parameters indicated that van der Waals interactions and hydrogen bonding occur between AMMP and DHBQ in MeOH.
The CHN, FTIR, and TG-DTA measurements confirmed that the solid HB-CT complex forms in a 2 : 1 ratio, i.e., [(AMMP)2(DHBQ)], and exhibits high stability.
Moreover, XRD analysis was used to establish that the mean particle size of the complex is 23 nm.
Finally, the solid HB-CT complex was screened for its antibacterial, antifungal, and antioxidant activities.
It shows good activity against various bacterial and fungal species.
Furthermore, the HB-CT complex exhibits good DPPH scavenging activity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Alghanmi, Reem M.. 2019. Synthesis, Characterization, and Biological Evaluation of a New Hydrogen-Bonded Charge-Transfer Complex of 2-Amino-4-methoxy-6-methylpyrimidine. Journal of Chemistry،Vol. 2019, no. 2019, pp.1-14.
https://search.emarefa.net/detail/BIM-1170645
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Alghanmi, Reem M.. Synthesis, Characterization, and Biological Evaluation of a New Hydrogen-Bonded Charge-Transfer Complex of 2-Amino-4-methoxy-6-methylpyrimidine. Journal of Chemistry No. 2019 (2019), pp.1-14.
https://search.emarefa.net/detail/BIM-1170645
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Alghanmi, Reem M.. Synthesis, Characterization, and Biological Evaluation of a New Hydrogen-Bonded Charge-Transfer Complex of 2-Amino-4-methoxy-6-methylpyrimidine. Journal of Chemistry. 2019. Vol. 2019, no. 2019, pp.1-14.
https://search.emarefa.net/detail/BIM-1170645
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1170645
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر