![](/images/graphics-bg.png)
Interplay between Body Size Measures and Thyroid Cancer Aggressiveness: A Retrospective Analysis
المؤلفون المشاركون
Zantut-Wittmann, Denise E.
Assumpção, Ligia Vera Montalli da
de Melo, Thaís Gomes
المصدر
International Journal of Endocrinology
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-08-27
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Considering controversial data about the relationship between body size and prognosis of differentiated thyroid cancer (DTC), the current study aimed to assess the influence of body weight, body mass index (BMI), and body surface area (BSA) on DTC.
We conducted a retrospective analysis of patients’ records from the Thyroid Cancer Unit, assessing body size measures, clinical and laboratory prognostic factors, and disease evolution.
337 patients, aged 45.95 ± 13.04 years old, with BMI of 27.87 ± 5.13 kg/m2 and BSA of 1.74 ± 0.18 m2 were enrolled.
After 9.5 ± 6.9 years of follow-up, 87.29% of patients were disease-free and 12.71% had persistent disease; no patient had deceased.
Patients aged <45 years old with extrathyroidal invasion tumor had greater baseline body weight and BSA than those without extrathyroidal invasion (median 79.5 kg versus 67 kg and 1.85 m2 versus 1.74 m2).
Women with poorly differentiated tumor and patients aged ≥45 years old with distant metastasis presented greater weight loss during follow-up compared to patients without such characteristics (median −2 kg versus +1.5 kg and −3 kg versus +1 kg, respectively).
The relationship between body size and DTC evolution was not observed.
In conclusion, higher weight and BSA were associated with a greater chance of extrathyroidal tumor invasion in younger patients.
Specific subgroups of patients with aggressive disease presented higher weight loss.
Young patients with higher BSA should be carefully treated due to possible worse prognosis related to increased incidence of extrathyroid invasion.
Findings related to tumor aggressiveness and weight loss in specific groups deserve further mechanistic studies.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
de Melo, Thaís Gomes& Assumpção, Ligia Vera Montalli da& Zantut-Wittmann, Denise E.. 2018. Interplay between Body Size Measures and Thyroid Cancer Aggressiveness: A Retrospective Analysis. International Journal of Endocrinology،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1171149
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
de Melo, Thaís Gomes…[et al.]. Interplay between Body Size Measures and Thyroid Cancer Aggressiveness: A Retrospective Analysis. International Journal of Endocrinology No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1171149
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
de Melo, Thaís Gomes& Assumpção, Ligia Vera Montalli da& Zantut-Wittmann, Denise E.. Interplay between Body Size Measures and Thyroid Cancer Aggressiveness: A Retrospective Analysis. International Journal of Endocrinology. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1171149
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1171149
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)