Gender-Specific Risk of Central Compartment Lymph Node Metastasis in Papillary Thyroid Carcinoma

المؤلفون المشاركون

Sun, Yushi
Zhang, Shaoqiang
Bai, Yanxia
Shi, Bingyin
Hongjun, Lv

المصدر

International Journal of Endocrinology

العدد

المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-7، 7ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2018-03-11

دولة النشر

مصر

عدد الصفحات

7

التخصصات الرئيسية

الأحياء

الملخص EN

Our aim was to evaluate the impact of gender on the predictive factors of central compartment lymph node metastasis (CLNM) in papillary thyroid carcinoma (PTC).

A retrospective study of 590 patients treated for PTC was performed.

Univariate and multivariate analyses showed that gender (female; P=0.001), age (≥45 y; P<0.001), tumor size (>1 cm; P<0.001), and multifocality (P=0.004) were independent predictive factors of CLNM in PTC patients.

Patients were divided into male group (n=152) and female group (n=438).

Age (≥45 y; P=0.001), T4 (P=0.006) and multifocality (P=0.024) were independent predictive risk factors of CLNM in male patients.

As for female patients, age (≥45 y; P<0.001), tumor size (>1 cm; P<0.001), multifocality (P=0.002), and microcalcification (P=0.027) were independently correlated with CLNM.

The sensitivity of the multivariate model for predicting CLNM in male patients was 64.9%, specificity was 82.9%, and area under the ROC curve (AUC) was 0.764.

As for female patients, the sensitivity was 55.7%, specificity was 77.9%, and AUC was 0.73.

This study showed that the predictive factors of CLNM indeed varied according to gender.

To have a more accurate evaluation of CLNM, different predictive systems should be used for male and female patients.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Sun, Yushi& Hongjun, Lv& Zhang, Shaoqiang& Bai, Yanxia& Shi, Bingyin. 2018. Gender-Specific Risk of Central Compartment Lymph Node Metastasis in Papillary Thyroid Carcinoma. International Journal of Endocrinology،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1171831

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Sun, Yushi…[et al.]. Gender-Specific Risk of Central Compartment Lymph Node Metastasis in Papillary Thyroid Carcinoma. International Journal of Endocrinology No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1171831

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Sun, Yushi& Hongjun, Lv& Zhang, Shaoqiang& Bai, Yanxia& Shi, Bingyin. Gender-Specific Risk of Central Compartment Lymph Node Metastasis in Papillary Thyroid Carcinoma. International Journal of Endocrinology. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1171831

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1171831