Gender-Specific Risk of Central Compartment Lymph Node Metastasis in Papillary Thyroid Carcinoma
Joint Authors
Sun, Yushi
Zhang, Shaoqiang
Bai, Yanxia
Shi, Bingyin
Hongjun, Lv
Source
International Journal of Endocrinology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-11
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Our aim was to evaluate the impact of gender on the predictive factors of central compartment lymph node metastasis (CLNM) in papillary thyroid carcinoma (PTC).
A retrospective study of 590 patients treated for PTC was performed.
Univariate and multivariate analyses showed that gender (female; P=0.001), age (≥45 y; P<0.001), tumor size (>1 cm; P<0.001), and multifocality (P=0.004) were independent predictive factors of CLNM in PTC patients.
Patients were divided into male group (n=152) and female group (n=438).
Age (≥45 y; P=0.001), T4 (P=0.006) and multifocality (P=0.024) were independent predictive risk factors of CLNM in male patients.
As for female patients, age (≥45 y; P<0.001), tumor size (>1 cm; P<0.001), multifocality (P=0.002), and microcalcification (P=0.027) were independently correlated with CLNM.
The sensitivity of the multivariate model for predicting CLNM in male patients was 64.9%, specificity was 82.9%, and area under the ROC curve (AUC) was 0.764.
As for female patients, the sensitivity was 55.7%, specificity was 77.9%, and AUC was 0.73.
This study showed that the predictive factors of CLNM indeed varied according to gender.
To have a more accurate evaluation of CLNM, different predictive systems should be used for male and female patients.
American Psychological Association (APA)
Sun, Yushi& Hongjun, Lv& Zhang, Shaoqiang& Bai, Yanxia& Shi, Bingyin. 2018. Gender-Specific Risk of Central Compartment Lymph Node Metastasis in Papillary Thyroid Carcinoma. International Journal of Endocrinology،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1171831
Modern Language Association (MLA)
Sun, Yushi…[et al.]. Gender-Specific Risk of Central Compartment Lymph Node Metastasis in Papillary Thyroid Carcinoma. International Journal of Endocrinology No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1171831
American Medical Association (AMA)
Sun, Yushi& Hongjun, Lv& Zhang, Shaoqiang& Bai, Yanxia& Shi, Bingyin. Gender-Specific Risk of Central Compartment Lymph Node Metastasis in Papillary Thyroid Carcinoma. International Journal of Endocrinology. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1171831
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1171831