Sheehan’s Syndrome Revisited: Underlying Autoimmunity or Hypoperfusion?
المؤلفون المشاركون
Rodríguez-Guajardo, René
González-González, José Gerardo
Rodríguez-Gutiérrez, René
Borjas-Almaguer, Omar David
Salcido-Montenegro, Alejandro
Elizondo-Plazas, Anasofia
Montes-de-Oca-Luna, Roberto
المصدر
International Journal of Endocrinology
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-02-26
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Sheehan’s syndrome remains a frequent obstetric complication with an uncertain pathophysiology.
We aimed to assess the incidence of hypopituitarism (≥2 hormonal axis impairment) within the first six postchildbirth months and to determine the existence of anti-pituitary antibodies.
From 2015 to 2017, adult pregnant women, who developed moderate to severe postpartum hemorrhage (PPH), were consecutively included in the study.
Pituitary function was assessed 4 and 24 weeks after PPH.
At the end of the study, anti-pituitary antibodies were assessed.
Twenty women completed the study.
Mean age was 26.35 (±5.83) years.
The main etiology for severe PPH was uterine atony (65%) which resulted mostly in hypovolemic shock grades III-IV.
Within the first four weeks after delivery, 95% of patients had at least one hormonal pituitary affected and 60% of the patients fulfilled diagnostic criteria for hypopituitarism.
At the end of the study period, five patients (25%) were diagnosed with hypopituitarism (GH and cortisol axes affected).
Anti-pituitary antibodies were negative in all patients.
At 6 months follow-up, one in every four women with a history of moderate-to-severe PPH was found with asymptomatic nonautoimmune-mediated hypopituitarism.
The role of autoimmunity in Sheehan’s syndrome remains uncertain.
Further studies are needed to improve the remaining knowledge gaps.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
González-González, José Gerardo& Borjas-Almaguer, Omar David& Salcido-Montenegro, Alejandro& Rodríguez-Guajardo, René& Elizondo-Plazas, Anasofia& Montes-de-Oca-Luna, Roberto…[et al.]. 2018. Sheehan’s Syndrome Revisited: Underlying Autoimmunity or Hypoperfusion?. International Journal of Endocrinology،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1172156
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
González-González, José Gerardo…[et al.]. Sheehan’s Syndrome Revisited: Underlying Autoimmunity or Hypoperfusion?. International Journal of Endocrinology No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1172156
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
González-González, José Gerardo& Borjas-Almaguer, Omar David& Salcido-Montenegro, Alejandro& Rodríguez-Guajardo, René& Elizondo-Plazas, Anasofia& Montes-de-Oca-Luna, Roberto…[et al.]. Sheehan’s Syndrome Revisited: Underlying Autoimmunity or Hypoperfusion?. International Journal of Endocrinology. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1172156
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1172156
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر