The Association between the Activin A Serum Level and Carotid Intima-Media Thickness in Chronic Kidney Disease Patients
المؤلفون المشاركون
Yonata, Ade
Ali, Zulkhair
Indrajaya, Taufik
Bahar, Erial
Effendi, Ian
Suhaimi, Novadian
Suprapti, Suprapti
المصدر
International Journal of Nephrology
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-11-09
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Introduction.
Chronic kidney disease (CKD) is associated with high mortality rates, mainly as a result of cardiovascular complications.
Meanwhile, recent studies have suggested a role of a homodimer protein called activin A in chronic kidney disease-mineral and bone disorder (CKD-MBD) conditions that may exist in the vascular calcification and osteolytic process.
Ultrasound examination of the carotid intima-media thickness (cIMT) is a noninvasive method to assess vascular calcification.
This study aimed to analyze the relationship between the activin A serum level and cIMT in patients with CKD at Mohammad Hoesin Hospital, Palembang, Indonesia.
Methods.
We conducted a hospital-based, cross-sectional study of consecutive CKD patients at the Department of Internal Medicine, Mohammad Hoesin Hospital, from July to November 2019.
The level of activin A was measured by enzyme-linked immunosorbent assay.
Meanwhile, cIMT measurements were collected by B-mode ultrasound imaging.
Results.
A total of 55 patients with CKD were included in this investigation.
The median serum activin A level in these patients was 236.17 (116.33–283) pg/mL, while the median cIMT was 0.8 (0.6–1.45) mm.
A relationship between the serum activin A level and cIMT (r = 0.449; p=0.001) was observed.
During multivariate analysis with linear regression, triglyceride p=0.049, phosphate p=0.005, and activin A p=0.020 serum levels were factors associated with cIMT.
Conclusion.
In this study, a relationship between the activin A serum level and cIMT in patients with CKD was identified.
Vascular calcification should be screened for in all CKD patients by the measurement of cIMT.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yonata, Ade& Ali, Zulkhair& Indrajaya, Taufik& Bahar, Erial& Effendi, Ian& Suhaimi, Novadian…[et al.]. 2020. The Association between the Activin A Serum Level and Carotid Intima-Media Thickness in Chronic Kidney Disease Patients. International Journal of Nephrology،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1172820
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yonata, Ade…[et al.]. The Association between the Activin A Serum Level and Carotid Intima-Media Thickness in Chronic Kidney Disease Patients. International Journal of Nephrology No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1172820
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yonata, Ade& Ali, Zulkhair& Indrajaya, Taufik& Bahar, Erial& Effendi, Ian& Suhaimi, Novadian…[et al.]. The Association between the Activin A Serum Level and Carotid Intima-Media Thickness in Chronic Kidney Disease Patients. International Journal of Nephrology. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1172820
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1172820
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر