The Association between Helicobacter pylori Infection and Glycated Hemoglobin A in Diabetes: A Meta-Analysis
المؤلفون المشاركون
Chen, Jinhu
Xing, Yuling
Zhao, Liying
Ma, Huijuan
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-09-09
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Background.
The association between Helicobacter pylori infection and glycated hemoglobin A has been confirmed in many studies, but these conclusions are still contradictory and controversial.
Therefore, we conducted a meta-analysis to resolve the problem of inconsistent results in diabetes.
Methods.
A comprehensive search was conducted on related researches published in PubMed, Embase, and China Academic Journal Full-text Database (CNKI) from the inception of each database to April 2019.
Fixed or random effects model was used to pool the weighted mean difference with 95% confidence interval from individual studies.
Subgroup and sensitivity analyses were also performed.
Publication bias was estimated by funnel plot, Egger’s test, and fail-safe numbers.
Results.
35 studies with 4,401 participants with diabetes were included in the meta-analysis.
Glycated hemoglobin A levels were elevated in patients with Helicobacter pylori infection compared with patients without Helicobacter pylori infection (WMD=0.50, 95% CI: 0.28-0.72, p<0.001).
In subgroup analysis by the subtype of diabetes, there was a correlation between Helicobacter pylori infection and elevated glycated hemoglobin A in type 1 diabetes (I2=74%, p<0.001, WMD=0.46, 95% CI: 0.12-0.80), and in type 2 diabetes (I2=90%, p<0.001, WMD=0.59, 95% CI: 0.28-0.90, p<0.001).
In subgroup analysis by the study design, there was a correlation in cross-sectional study (I2=89%, p<0.001, WMD=0.42, 95% CI: 0.16-0.69, p≤0.003) and in case-control study (I2=83%, p<0.001, WMD=0.39, 95% CI: 0.14-0.64, p≤0.003).
By different methods for detecting Helicobacter pylori, there was a correlation in the biopsy group (I2=83%, p<0.001, WMD=0.6, 95% CI: 0.11-1.09, p≤0.03) and in other groups of test methods (I2=87%, p<0.001, WMD=0.37, 95% CI: 0.17-0.56, p<0.001).
Sensitivity analysis showed that our results were reliable, and no evidence of substantial publication bias was detected.
Conclusion.
The meta-analysis might indicate a correlation between Helicobacter pylori infection and glycated hemoglobin A levels in diabetes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chen, Jinhu& Xing, Yuling& Zhao, Liying& Ma, Huijuan. 2019. The Association between Helicobacter pylori Infection and Glycated Hemoglobin A in Diabetes: A Meta-Analysis. Journal of Diabetes Research،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1172889
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chen, Jinhu…[et al.]. The Association between Helicobacter pylori Infection and Glycated Hemoglobin A in Diabetes: A Meta-Analysis. Journal of Diabetes Research No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1172889
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chen, Jinhu& Xing, Yuling& Zhao, Liying& Ma, Huijuan. The Association between Helicobacter pylori Infection and Glycated Hemoglobin A in Diabetes: A Meta-Analysis. Journal of Diabetes Research. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1172889
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1172889
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر