Presenting a New Standard Drug Model for Turmeric and Its Prized Extract, Curcumin
المؤلف
المصدر
International Journal of Inflammation
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-18، 18ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-01-15
دولة النشر
مصر
عدد الصفحات
18
التخصصات الرئيسية
الملخص EN
Various parts of the turmeric plant have been used as medicinal treatment for various conditions from ulcers and arthritis to cardiovascular disease and neuroinflammation.
The rhizome’s curcumin extract is the most studied active constituent, which exhibits an expansive polypharmacology with influence on many key inflammatory markers.
Despite the expansive reports of curcucmin’s therapeutic value, clinical reliability and research repeatability with curcumin treatment are still poor.
The pharmacology must be better understood and reliably mapped if curcumin is to be accepted and used in modern medical applications.
Although the polypharmacology of this extract has been considered, in mainstream medicine, to be a drawback, a perspective change reveals a comprehensive and even synergistic shaping of the NF-kB pathway, including transactivation.
Much of the inconsistent research data and unreliable clinical outcomes may be due to a lack of standardization which also pervades research standard samples.
The possibility of other well-known curcumin by-products contributing in the polypharmacology is also discussed.
A new flowchart of crosstalk in transduction pathways that lead to shaping of nuclear NF-kB transactivation is generated and a new calibration or standardization protocol for the extract is proposed which could lead to more consistent data extraction and improved reliability in therapy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cavaleri, Franco. 2018. Presenting a New Standard Drug Model for Turmeric and Its Prized Extract, Curcumin. International Journal of Inflammation،Vol. 2018, no. 2018, pp.1-18.
https://search.emarefa.net/detail/BIM-1173251
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cavaleri, Franco. Presenting a New Standard Drug Model for Turmeric and Its Prized Extract, Curcumin. International Journal of Inflammation No. 2018 (2018), pp.1-18.
https://search.emarefa.net/detail/BIM-1173251
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cavaleri, Franco. Presenting a New Standard Drug Model for Turmeric and Its Prized Extract, Curcumin. International Journal of Inflammation. 2018. Vol. 2018, no. 2018, pp.1-18.
https://search.emarefa.net/detail/BIM-1173251
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1173251
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر