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Effects of Exercise Training and Weight Loss on Plasma Fetuin-A Levels and Insulin Sensitivity in Overweight Older Men
المؤلفون المشاركون
Blumenthal, Jacob B.
Gitterman, Anna
Ryan, Alice S.
Prior, Steven J.
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-07-09
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Aerobic exercise training and weight loss (AEX+WL) improves insulin sensitivity in overweight adults; however, the underlying pathways are incompletely understood.
Fetuin-A, a hepatokine that inhibits insulin signaling, may be involved in the salutary effects of AEX+WL.
Therefore, we examined the effects of 6-month AEX+WL on plasma fetuin-A levels (36–48 hours after the last bout of exercise), aerobic capacity (VO2max), body composition, glucose tolerance, and insulin sensitivity (M) in 16 sedentary, overweight-obese older men (age = 60 ± 2 years, BMI = 31 ± 1 kg/m2) with no history of cardiovascular disease or diabetes.
At baseline, fetuin-A levels correlated directly with adiposity and had a borderline inverse correlation with M.
After AEX+WL, body weight decreased by ~10 kg, while both VO2max and M increased by 16% (P<0.005 for all).
Contrary to our hypothesis, plasma fetuin-A levels increased after AEX+WL (1.16 ± 0.10 g/L versus 1.70 ± 0.19 g/L, P=0.006).
This increase was unrelated to changes in body composition or glucose metabolism, but directly correlated with changes in VO2max (r=0.57, P<0.05).
Thus, in overweight-to-obese older men, AEX+WL appears to increase plasma fetuin-A levels.
Although not associated with improvements in insulin sensitivity, this increase in fetuin-A was related to improvements in aerobic capacity and could be representative of the cardioprotective effects of AEX+WL in older men.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Blumenthal, Jacob B.& Gitterman, Anna& Ryan, Alice S.& Prior, Steven J.. 2017. Effects of Exercise Training and Weight Loss on Plasma Fetuin-A Levels and Insulin Sensitivity in Overweight Older Men. Journal of Diabetes Research،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1173811
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Blumenthal, Jacob B.…[et al.]. Effects of Exercise Training and Weight Loss on Plasma Fetuin-A Levels and Insulin Sensitivity in Overweight Older Men. Journal of Diabetes Research No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1173811
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Blumenthal, Jacob B.& Gitterman, Anna& Ryan, Alice S.& Prior, Steven J.. Effects of Exercise Training and Weight Loss on Plasma Fetuin-A Levels and Insulin Sensitivity in Overweight Older Men. Journal of Diabetes Research. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1173811
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1173811
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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