The Role of Mannose-Binding Lectin Serum Level in Tubotympanic Chronic Suppurative Otitis Media
المؤلفون المشاركون
Surono, Agus
Darmawan, Anton Budhi
Soesatyo, Marsetyawan H. N. E.
Restuti, Ratna Dwi
المصدر
International Journal of Otolaryngology
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-05-22
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Background.
Chronic suppurative otitis media (CSOM) is a common public health problem worldwide and a major cause of hearing impairment especially in developing countries.
The role of Mannose-Binding Lectin (MBL), a component of innate immunity, in CSOM has not been studied.
The aim of the study was to examine whether MBL deficiency was more frequently present in cases group of tubotympanic CSOM patients rather than healthy subjects.
Material and Methods.
This was an analytic observational study.
Subjects were enrolled in the Otorhinolaryngology Clinic at Margono Soekarjo Hospital, Purwokerto, Indonesia.
An independent t-test was used to compare the mean of MBL serum concentration between tubotympanic CSOM subjects and control.
Results.
From 36 tubotympanic CSOM patients, there were 8 (22.22%) patients with MBL deficiency (MBL level < 100 ng/ml), while no deficiency was found in the control group.
The mean of MBL level in cases group was 354.88 ng/ml, with the lowest level being 0.001 ng/ml and the highest level 690.24 ng/ml, while in the control group MBL level mean was 376.27 with the lowest level being 188.71 and the highest level 794.54 ng/ml.
Conclusion.
There was no significant difference of MBL serum level between tubotympanic CSOM and control group.
However, the presence of subjects with MBL deficiency in the tubotympanic CSOM group might be considered as playing a role in the tubotympanic CSOM.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Darmawan, Anton Budhi& Soesatyo, Marsetyawan H. N. E.& Restuti, Ratna Dwi& Surono, Agus. 2018. The Role of Mannose-Binding Lectin Serum Level in Tubotympanic Chronic Suppurative Otitis Media. International Journal of Otolaryngology،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1173846
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Darmawan, Anton Budhi…[et al.]. The Role of Mannose-Binding Lectin Serum Level in Tubotympanic Chronic Suppurative Otitis Media. International Journal of Otolaryngology No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1173846
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Darmawan, Anton Budhi& Soesatyo, Marsetyawan H. N. E.& Restuti, Ratna Dwi& Surono, Agus. The Role of Mannose-Binding Lectin Serum Level in Tubotympanic Chronic Suppurative Otitis Media. International Journal of Otolaryngology. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1173846
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1173846
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر