Clinical and Immunological Profile of Mixed Connective Tissue Disease and a Comparison of Four Diagnostic Criteria
المؤلفون المشاركون
John, Kevin
Gunasekaran, Karthik
Sadiq, Mohammad
George, Tina
Francis, Nirmal
Rajadurai, Ebenezer
Sudarsanam, Thambu David
المصدر
International Journal of Rheumatology
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-01-29
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Mixed connective tissue disease (MCTD) was initially described as a chronic immune-mediated disease with overlapping features of systemic lupus erythematosus, scleroderma, and polymyositis.
We conducted a cross-sectional study to describe the clinical and immunological profile of patients with MCTD and to compare the four diagnostic criteria, namely, Sharp, Kasukawa, Alarcón-Segovia, and Khan criteria.
A total of 291 patients who were admitted from June 2007 to June 2017 and fulfilled the inclusion criteria were included in the study.
A clinical diagnosis of MCTD was made in 111 patients, of whom 103 (92.8%) were women.
The mean age at presentation was 39.3 years (SD±11.6).
The most common organ systems that were involved were musculoskeletal system (95.5%), skin and mucosa (78.4%), and the gastrointestinal and hepatobiliary systems (56%).
The maximum sensitivity was for the Kasukawa criteria with a sensitivity of 77.5% (95% CI 68.4-84.6) and specificity of 92.2% (95% CI 87-95.5).
The Kahn criteria and Alarcón-Segovia criteria had the maximum specificity; the Alarcón-Segovia criteria had a sensitivity of 69.4% (95% CI 59.8-77.6) and a specificity of 99.4% (95% CI 96.5-99.9), while the Kahn criteria had a sensitivity of 52.3% (95% CI 42.6-61.7) and a specificity of 99.4% (95% CI 96.5-99.9).
The sensitivity and specificity of Sharp criteria were 57.7% (95% CI 47.9-66.87) and 90% (95% CI 84.4-93.8), respectively.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
John, Kevin& Sadiq, Mohammad& George, Tina& Gunasekaran, Karthik& Francis, Nirmal& Rajadurai, Ebenezer…[et al.]. 2020. Clinical and Immunological Profile of Mixed Connective Tissue Disease and a Comparison of Four Diagnostic Criteria. International Journal of Rheumatology،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1173995
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
John, Kevin…[et al.]. Clinical and Immunological Profile of Mixed Connective Tissue Disease and a Comparison of Four Diagnostic Criteria. International Journal of Rheumatology No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1173995
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
John, Kevin& Sadiq, Mohammad& George, Tina& Gunasekaran, Karthik& Francis, Nirmal& Rajadurai, Ebenezer…[et al.]. Clinical and Immunological Profile of Mixed Connective Tissue Disease and a Comparison of Four Diagnostic Criteria. International Journal of Rheumatology. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1173995
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1173995
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر