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Urinary Sodium Concentration Is an Independent Predictor of All-Cause and Cardiovascular Mortality in a Type 2 Diabetes Cohort Population
المؤلفون المشاركون
Halimi, Jean-Michel
Saulnier, Pierre-Jean
Gand, Elise
Ragot, Stéphanie
Bankir, Lise
Piguel, Xavier
Fumeron, Frédéric
Marechaud, Richard
Roussel, Ronan
Hadjadj, Samy
Study group, SURDIAGENE
Rigalleau, Vincent
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-02-01
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Objective.
Sodium intake is associated with cardiovascular outcomes.
However, no study has specifically reported an association between cardiovascular mortality and urinary sodium concentration (UNa).
We examined the association of UNa with mortality in a cohort of type 2 diabetes (T2D) patients.
Methods.
Patients were followed for all-cause death and cardiovascular death.
Baseline UNa was measured from second morning spot urinary sample.
We used Cox proportional hazard models to identify independent predictors of mortality.
Improvement in prediction of mortality by the addition of UNa to a model including known risk factors was assessed by the relative integrated discrimination improvement (rIDI) index.
Results.
Participants (n=1,439) were followed for a median of 5.7 years, during which 254 cardiovascular deaths and 429 all-cause deaths were recorded.
UNa independently predicted all-cause and cardiovascular mortality.
An increase of one standard deviation of UNa was associated with a decrease of 21% of all-cause mortality and 22% of cardiovascular mortality.
UNa improved all-cause and cardiovascular mortality prediction beyond identified risk factors (rIDI = 2.8%, P=0.04 and rIDI = 4.6%, P=0.02, resp.).
Conclusions.
In T2D, UNa was an independent predictor of mortality (low concentration is associated with increased risk) and improved modestly its prediction in addition to traditional risk factors.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Saulnier, Pierre-Jean& Gand, Elise& Ragot, Stéphanie& Bankir, Lise& Piguel, Xavier& Fumeron, Frédéric…[et al.]. 2017. Urinary Sodium Concentration Is an Independent Predictor of All-Cause and Cardiovascular Mortality in a Type 2 Diabetes Cohort Population. Journal of Diabetes Research،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1174434
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Saulnier, Pierre-Jean…[et al.]. Urinary Sodium Concentration Is an Independent Predictor of All-Cause and Cardiovascular Mortality in a Type 2 Diabetes Cohort Population. Journal of Diabetes Research No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1174434
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Saulnier, Pierre-Jean& Gand, Elise& Ragot, Stéphanie& Bankir, Lise& Piguel, Xavier& Fumeron, Frédéric…[et al.]. Urinary Sodium Concentration Is an Independent Predictor of All-Cause and Cardiovascular Mortality in a Type 2 Diabetes Cohort Population. Journal of Diabetes Research. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1174434
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1174434
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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