Radical Gastrectomy: Still the Cornerstone of Curative Treatment for Gastric Cancer in the Perioperative Chemotherapy Era—A Single Institute Experience over a Decade
المؤلفون المشاركون
Kanhere, Harsh
Goel, Raghav
Finlay, Ben
Trochsler, Markus
Maddern, Guy J.
المصدر
International Journal of Surgical Oncology
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-01-14
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background and Objectives.
Most gastric cancer patients now undergo perioperative chemotherapy (POCT) based on the MAGIC trial results.
POCT consists of neoadjuvant chemotherapy (NACT) as well as postoperative adjuvant chemotherapy.
This study assessed the applicability of perioperative chemotherapy and the impact of radical gastrectomy encompassing a detailed lymph-node resection on outcomes of gastric cancer.
Methods.
Medical and pathology records of all gastric carcinoma resections were reviewed from 2006 onwards.
Pathological details, number of lymph-nodes resected, and proportion of involved nodes, reasons for nonadministration of NACT, complications, recurrence, and survival data were analysed.
Results.
Only twenty-eight (37.8%) out of 74 patients underwent NACT and only nine completed POCT.
NACT was declined due to comorbidities/patient refusal n=24, early stage n=14, and emergency presentation n=8.
Patients receiving NACT were much younger.
Anastomotic leaks, hospital-mortality, lymph-node yield, and proportion of involved lymph-nodes were similar in both groups.
Thirty-two patients died due to recurrence with lymph-node involvement heralding higher recurrence risk and much poorer survival (HR 2.66; p=0.013).
Conclusion.
More than 60% patients with resectable gastric carcinoma did not undergo NACT.
Radical gastrectomy with lymphadenectomy remained the cornerstone of treatment in this period.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kanhere, Harsh& Goel, Raghav& Finlay, Ben& Trochsler, Markus& Maddern, Guy J.. 2018. Radical Gastrectomy: Still the Cornerstone of Curative Treatment for Gastric Cancer in the Perioperative Chemotherapy Era—A Single Institute Experience over a Decade. International Journal of Surgical Oncology،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1175699
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kanhere, Harsh…[et al.]. Radical Gastrectomy: Still the Cornerstone of Curative Treatment for Gastric Cancer in the Perioperative Chemotherapy Era—A Single Institute Experience over a Decade. International Journal of Surgical Oncology No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1175699
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kanhere, Harsh& Goel, Raghav& Finlay, Ben& Trochsler, Markus& Maddern, Guy J.. Radical Gastrectomy: Still the Cornerstone of Curative Treatment for Gastric Cancer in the Perioperative Chemotherapy Era—A Single Institute Experience over a Decade. International Journal of Surgical Oncology. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1175699
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1175699
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر