Study of the Mechanical Environment of Chondrocytes in Articular Cartilage Defects Repaired Area under Cyclic Compressive Loading
المؤلفون المشاركون
Wei, Wang
Zhang, Chunqiu
Liu, Hai-Ying
Duan, Hang-Tian
المصدر
Journal of Healthcare Engineering
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-07-09
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
COMSOL finite element software was used to establish a solid-liquid coupling biphasic model of articular cartilage and a microscopic model of chondrocytes, using modeling to take into account the shape and number of chondrocytes in cartilage lacuna in each layer.
The effects of cyclic loading at different frequencies on the micromechanical environment of chondrocytes in different regions of the cartilage were studied.
The results showed that low frequency loading can cause stress concentration of superficial chondrocytes.
Moreover, along with increased frequency, the maximum value of stress response curve of chondrocytes decreased, while the minimum value increased.
When the frequency was greater than 0.2 Hz, the extreme value stress of response curve tended to be constant.
Cyclic loading had a large influence on the distribution of liquid pressure in chondrocytes in the middle and deep layers.
The concentration of fluid pressure changed alternately from intracellular to peripheral in the middle layer.
Both the range of liquid pressure in the upper chondrocytes and the maximum value of liquid pressure in the lower chondrocytes in the same lacunae varied greatly in the deep layer.
At the same loading frequency, the elastic modulus of artificial cartilage had little effect on the mechanical environment of chondrocytes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Liu, Hai-Ying& Duan, Hang-Tian& Zhang, Chunqiu& Wei, Wang. 2017. Study of the Mechanical Environment of Chondrocytes in Articular Cartilage Defects Repaired Area under Cyclic Compressive Loading. Journal of Healthcare Engineering،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1180779
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Liu, Hai-Ying…[et al.]. Study of the Mechanical Environment of Chondrocytes in Articular Cartilage Defects Repaired Area under Cyclic Compressive Loading. Journal of Healthcare Engineering No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1180779
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Liu, Hai-Ying& Duan, Hang-Tian& Zhang, Chunqiu& Wei, Wang. Study of the Mechanical Environment of Chondrocytes in Articular Cartilage Defects Repaired Area under Cyclic Compressive Loading. Journal of Healthcare Engineering. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1180779
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1180779
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر