Associations between ACE-Inhibitors, Angiotensin Receptor Blockers, and Lean Body Mass in Community Dwelling Older Women
المؤلفون المشاركون
Wassertheil-Smoller, Sylvia
LaCroix, Andrea Z.
Bea, Jennifer W.
Wertheim, Betsy C.
Klimentidis, Yann
Chen, Zhao
Zaslavsky, Oleg
Manini, Todd M.
Womack, Catherine R.
Kroenke, Candyce H.
Thomson, Cynthia A.
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-02-19
دولة النشر
مصر
عدد الصفحات
8
الملخص EN
Studies suggest that ACE-inhibitors (ACE-I) and angiotensin receptor blockers (ARBs) may preserve skeletal muscle with aging.
We evaluated longitudinal differences in lean body mass (LBM) among women diagnosed with hypertension and classified as ACE-I/ARB users and nonusers among Women’s Health Initiative participants that received dual energy X-ray absorptiometry scans to estimate body composition (n=10,635) at baseline and at years 3 and 6 of follow-up.
Of those, 2642 were treated for hypertension at baseline.
Multivariate linear regression models, adjusted for relevant demographics, behaviors, and medications, assessed ACE-I/ARB use/nonuse and LBM associations at baseline, as well as change in LBM over 3 and 6 years.
Although BMI did not differ by ACE-I/ARB use, LBM (%) was significantly higher in ACE-I/ARB users versus nonusers at baseline (52.2% versus 51.3%, resp., p=0.001).
There was no association between ACE-I/ARB usage and change in LBM over time.
Reasons for higher LBM with ACE-I/ARB use cross sectionally, but not longitundinally, are unclear and may reflect a threshold effect of these medications on LBM that is attenuated over time.
Nevertheless, ACE-I/ARB use does not appear to negatively impact LBM in the long term.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bea, Jennifer W.& Wassertheil-Smoller, Sylvia& Wertheim, Betsy C.& Klimentidis, Yann& Chen, Zhao& Zaslavsky, Oleg…[et al.]. 2018. Associations between ACE-Inhibitors, Angiotensin Receptor Blockers, and Lean Body Mass in Community Dwelling Older Women. Journal of Aging Research،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1180782
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bea, Jennifer W.…[et al.]. Associations between ACE-Inhibitors, Angiotensin Receptor Blockers, and Lean Body Mass in Community Dwelling Older Women. Journal of Aging Research No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1180782
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bea, Jennifer W.& Wassertheil-Smoller, Sylvia& Wertheim, Betsy C.& Klimentidis, Yann& Chen, Zhao& Zaslavsky, Oleg…[et al.]. Associations between ACE-Inhibitors, Angiotensin Receptor Blockers, and Lean Body Mass in Community Dwelling Older Women. Journal of Aging Research. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1180782
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1180782
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر