Gentamicin Released from Porous Scaffolds Fabricated by Stereolithography
المؤلفون المشاركون
Channasanon, Somruethai
Udomkusonsri, Pareeya
Chantaweroad, Surapol
Tesavibul, Passakorn
Tanodekaew, Siriporn
المصدر
Journal of Healthcare Engineering
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-08-20
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Porous oligolactide-hydroxyapatite composite scaffolds were obtained by stereolithographic fabrication.
Gentamicin was then coated on the scaffolds afterwards, to achieve antimicrobial delivery ability to treat bone infection.
The scaffolds examined by stereomicroscope, SEM, and μCT-scan showed a well-ordered pore structure with uniform pore distribution and pore interconnectivity.
The physical and mechanical properties of the scaffolds were investigated.
It was shown that not only porosity but also scaffold structure played a critical role in governing the strength of scaffolds.
A good scaffold design could create proper orientation of pores in a way to strengthen the scaffold structure.
The drug delivery profile of the porous scaffolds was also analyzed using microbiological assay.
The release rates of gentamicin from the scaffolds showed prolonged drug release at the levels higher than the minimum inhibitory concentrations for S.
aureus and E.
coli over a 2-week period.
It indicated a potential of the scaffolds to serve as local antibiotic delivery to prevent bacterial infection.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Channasanon, Somruethai& Udomkusonsri, Pareeya& Chantaweroad, Surapol& Tesavibul, Passakorn& Tanodekaew, Siriporn. 2017. Gentamicin Released from Porous Scaffolds Fabricated by Stereolithography. Journal of Healthcare Engineering،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1181425
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Channasanon, Somruethai…[et al.]. Gentamicin Released from Porous Scaffolds Fabricated by Stereolithography. Journal of Healthcare Engineering No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1181425
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Channasanon, Somruethai& Udomkusonsri, Pareeya& Chantaweroad, Surapol& Tesavibul, Passakorn& Tanodekaew, Siriporn. Gentamicin Released from Porous Scaffolds Fabricated by Stereolithography. Journal of Healthcare Engineering. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1181425
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1181425
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر