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Effect of Surface Charge and Hydrophobicity Modulation on the Antibacterial and Antibiofilm Potential of Magnetic Iron Nanoparticles
المؤلفون المشاركون
Shebl, Rania Ibrahim
Farouk, Faten
Azzazy, Hassan Mohamed El-Said
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-15، 15ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-09-12
دولة النشر
مصر
عدد الصفحات
15
التخصصات الرئيسية
الملخص EN
Unmodified magnetic nanoparticles (MNPs) lack antibacterial potential.
We investigated MNPs surface modifications that can impart antibacterial activity.
Six MNPs species were prepared and characterized.
Their antibacterial and antibiofilm potentials, surface affinity, and cytotoxicity were evaluated.
Prepared MNPs were functionalized with citric acid, amine group, amino-propyl trimethoxy silane (APTMS), arginine, or oleic acid (OA) to give hydrophilic and hydrophobic MNPs with surface charge ranging from −30 to +30 mV.
Prepared MNPs were spherical in shape with an average size of 6–15 nm.
Hydrophobic (OA-MNPs) and positively charged MNPs (APTMS-MNPs) had significant concentration dependent antibacterial effect.
OA-MNPs showed higher inhibitory potential against S.
aureus and E.
coli (80%) than APTMS-MNPs (70%).
Both particles exhibited surface affinity to S.
aureus and E.
coli.
Different concentrations of OA-MNPs decreased S.
aureus and E.
coli biofilm formation by 50–90%, while APTMS-MNPs reduced it by 30–90%, respectively.
Up to 90% of preformed biofilms of S.
aureus and E.
coli were destroyed by OA-MNPs and APTMS-MNPs.
In conclusion, surface positivity and hydrophobicity enhance antibacterial and antibiofilm properties of MNPs.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Shebl, Rania Ibrahim& Farouk, Faten& Azzazy, Hassan Mohamed El-Said. 2017. Effect of Surface Charge and Hydrophobicity Modulation on the Antibacterial and Antibiofilm Potential of Magnetic Iron Nanoparticles. Journal of Nanomaterials،Vol. 2017, no. 2017, pp.1-15.
https://search.emarefa.net/detail/BIM-1182900
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Shebl, Rania Ibrahim…[et al.]. Effect of Surface Charge and Hydrophobicity Modulation on the Antibacterial and Antibiofilm Potential of Magnetic Iron Nanoparticles. Journal of Nanomaterials No. 2017 (2017), pp.1-15.
https://search.emarefa.net/detail/BIM-1182900
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Shebl, Rania Ibrahim& Farouk, Faten& Azzazy, Hassan Mohamed El-Said. Effect of Surface Charge and Hydrophobicity Modulation on the Antibacterial and Antibiofilm Potential of Magnetic Iron Nanoparticles. Journal of Nanomaterials. 2017. Vol. 2017, no. 2017, pp.1-15.
https://search.emarefa.net/detail/BIM-1182900
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1182900
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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