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Arterial Stiffness Is Associated with Peripheral Sensory Neuropathy in Diabetes Patients in Ghana
المؤلفون المشاركون
Yeboah, Kwame
Kormla Affrim, Patrick
Agyekum, Jennifer A.
Adjei, Afua B.
Owusu Mensah, Richard N. A.
Adu-Gyamfi, Linda
Doughan, Rita O.
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-01-31
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Objective.
Peripheral sensory neuropathy (PSN) is among microvascular complications of diabetes that make patients prone to ulceration and amputation.
Arterial stiffness is a predictor of cardiovascular diseases and microvascular complications associated with diabetes.
We investigated the association between PSN and arterial stiffness, measured as aortic pulse wave velocity (PWVao) and cardio-ankle vascular index (CAVI).
Method.
In a case-control design, arterial stiffness was measured in 240 diabetes patients and 110 nondiabetic control.
Large-fibre nerve function was assessed by vibration perception threshold (VPT) using a neurothesiometer.
PSN was defined as the VPT > 97.5th percentile from age- and gender-adjusted models in nondiabetic controls.
Results.
The overall prevalence of PSN was 16.6% in the entire study participants.
Compared to non-PSN participants, PSN patients had higher levels of PWVao (9.5 ± 1.7 versus 8.7 ± 1.2 m/s, p=0.016) and CAVI (8.4 ± 1.3 versus 7.6 ± 1.1, p=0.001).
In multiple regression models, VPT was associated with PWVao (β=0.14, p=0.025) and CAVI (β=0.12, p=0.04).
PSN patients had increased odds of CAVI (OR = 1.51 (1.02–2.4), p=0.043), but not PWVao (OR = 1.25 (0.91–1.71), p=0.173).
Conclusion.
PWVao and CAVI were associated with VPT and PSN in diabetes patients in Ghana.
Patients having PSN have increased odds of CAVI, independent of other conventional risk factors.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yeboah, Kwame& Agyekum, Jennifer A.& Owusu Mensah, Richard N. A.& Kormla Affrim, Patrick& Adu-Gyamfi, Linda& Doughan, Rita O.…[et al.]. 2018. Arterial Stiffness Is Associated with Peripheral Sensory Neuropathy in Diabetes Patients in Ghana. Journal of Diabetes Research،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1183351
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yeboah, Kwame…[et al.]. Arterial Stiffness Is Associated with Peripheral Sensory Neuropathy in Diabetes Patients in Ghana. Journal of Diabetes Research No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1183351
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yeboah, Kwame& Agyekum, Jennifer A.& Owusu Mensah, Richard N. A.& Kormla Affrim, Patrick& Adu-Gyamfi, Linda& Doughan, Rita O.…[et al.]. Arterial Stiffness Is Associated with Peripheral Sensory Neuropathy in Diabetes Patients in Ghana. Journal of Diabetes Research. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1183351
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1183351
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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