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The Threshold of the Severity of Diabetic Retinopathy below Which Intensive Glycemic Control Is Beneficial in Diabetic Patients: Estimation Using Data from Large Randomized Clinical Trials
المؤلفون المشاركون
Tong, Nanwei
Liu, Yuqi
Li, Juan
Ma, Jinfang
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-01-17
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Intensive glucose therapy can protect the retina of individuals with diabetes, but it is unknown if it provides the same protection to patients with different severity of diabetic retinopathy (DR).
We finally included DR-related studies involving intensive glucose control with large sample size and long follow-up time, including five large and high-quality randomized clinical trials (RCTs): DCCT, UKPDS, ACCORD, AdRem, and VADT.
With DCCT as a reference, we supposed a DR severity threshold that is verified by other RCTs then.
We found that individuals who have DR lesions that are equivalent to or less severe than moderate NPDR achieve benefits for the retina by intensive glycemic control.
However, these are realized only if the HbA1c in type 1 or type 2 diabetic patients is reduced at least by 0.8% versus the control group or it is reduced to <7% and >3 years of intensive glucose control is required.
If the severity of DR lesions is worse than moderate NPDR, intensive glycemic control may not bring benefits.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Liu, Yuqi& Li, Juan& Ma, Jinfang& Tong, Nanwei. 2020. The Threshold of the Severity of Diabetic Retinopathy below Which Intensive Glycemic Control Is Beneficial in Diabetic Patients: Estimation Using Data from Large Randomized Clinical Trials. Journal of Diabetes Research،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1183470
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Liu, Yuqi…[et al.]. The Threshold of the Severity of Diabetic Retinopathy below Which Intensive Glycemic Control Is Beneficial in Diabetic Patients: Estimation Using Data from Large Randomized Clinical Trials. Journal of Diabetes Research No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1183470
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Liu, Yuqi& Li, Juan& Ma, Jinfang& Tong, Nanwei. The Threshold of the Severity of Diabetic Retinopathy below Which Intensive Glycemic Control Is Beneficial in Diabetic Patients: Estimation Using Data from Large Randomized Clinical Trials. Journal of Diabetes Research. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1183470
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1183470
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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