Addressing Stem Cell Therapeutic Approaches in Pathobiology of Diabetes and Its Complications
المؤلفون المشاركون
Dubey, Navneet Kumar
Wei, Hong-Jian
Peng, Boe-Yu
Deng, Win-Ping
Mishra, Viraj Krishna
Tsai, Feng-Chou
Dubey, Rajni
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-16، 16ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-06-25
دولة النشر
مصر
عدد الصفحات
16
التخصصات الرئيسية
الملخص EN
High morbidity and mortality of diabetes mellitus (DM) throughout the human population is a serious threat which needs to be addressed cautiously.
Type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) are most prevalent forms.
Disruption in insulin regulation and resistance leads to increased formation and accumulation of advanced end products (AGEs), which further enhance oxidative and nitrosative stress leading to microvascular (retinopathy, neuropathy, and nephropathy) and macrovascular complications.
These complications affect the normal function of organ and tissues and may cause life-threatening disorders, if hyperglycemia persists and improperly controlled.
Current and traditional treatment procedures are only focused on to regulate the insulin level and do not cure the diabetic complications.
Pancreatic transplantation seemed a viable alternative; however, it is limited due to lack of donors.
Cell-based therapy such as stem cells is considered as a promising therapeutic agent against DM and diabetic complications owing to their multilineage differentiation and regeneration potential.
Previous studies have demonstrated the various impacts of both pluripotent and multipotent stem cells on DM and its micro- and macrovascular complications.
Therefore, this review summarizes the potential of stem cells to treat DM and its related complications.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Peng, Boe-Yu& Dubey, Navneet Kumar& Mishra, Viraj Krishna& Tsai, Feng-Chou& Dubey, Rajni& Deng, Win-Ping…[et al.]. 2018. Addressing Stem Cell Therapeutic Approaches in Pathobiology of Diabetes and Its Complications. Journal of Diabetes Research،Vol. 2018, no. 2018, pp.1-16.
https://search.emarefa.net/detail/BIM-1183901
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Peng, Boe-Yu…[et al.]. Addressing Stem Cell Therapeutic Approaches in Pathobiology of Diabetes and Its Complications. Journal of Diabetes Research No. 2018 (2018), pp.1-16.
https://search.emarefa.net/detail/BIM-1183901
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Peng, Boe-Yu& Dubey, Navneet Kumar& Mishra, Viraj Krishna& Tsai, Feng-Chou& Dubey, Rajni& Deng, Win-Ping…[et al.]. Addressing Stem Cell Therapeutic Approaches in Pathobiology of Diabetes and Its Complications. Journal of Diabetes Research. 2018. Vol. 2018, no. 2018, pp.1-16.
https://search.emarefa.net/detail/BIM-1183901
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1183901
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر