Do Insulin Replacement and Omega3 Protect the Male Reproductive Function of the Streptozotocin-Induced Diabetic Mice?
المؤلفون المشاركون
Yaghoubi, Atefe
Shahedi, Abbas
Akbari, Hakime
Nematollahi-Mahani, Seyed Noureddin
المصدر
Journal of Nutrition and Metabolism
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-07-10
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Diabetes mellitus (DM), the most common metabolic disease, might affect different organs such as male reproductive system.
Experiments have shown that n-3 fatty acids could improve male reproductive function.
Present study was performed to examine the effects of omega3 on sperms and testicular parameters in diabetic mice.
Adult NMRI male mice were randomly divided into intact and diabetic groups (n=8).
Streptozotocin-induced diabetic animals were divided into 4 groups of diabetic-saline (Dia-Sa), diabetic-insulin (Dia-Ins), diabetic-omega3 (Dia-omg3), and diabetic-insulin-omega3 (Dia-Ins-omg3).
Following confirmation of diabetes, different treatments including 3 U/100 g insulin subcutaneously and 400 mg/kg omega3 orally were administered, where applicable according to the treatment groups.
Thirty-five days later, the sperm number, motility, progression, and normal morphology were determined.
Also, testes diameters and structure including germinal epithelium thickness, seminiferous tubule diameters, Leydig cell number, and testosterone level were assessed.
Sperm number, viability, fast motility, testes volume, and serum testosterone level decreased insignificantly in the Dia-Sa group compared with the intact animals.
Neither insulin replacement nor omega3 administration could significantly improve the outcome.
We might conclude that short periods of diabetes could not significantly affect the male reproductive function.
In addition, insulin replacement and/or omega-3 supplementation does not have any profound effects on male reproductive system.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yaghoubi, Atefe& Shahedi, Abbas& Akbari, Hakime& Nematollahi-Mahani, Seyed Noureddin. 2017. Do Insulin Replacement and Omega3 Protect the Male Reproductive Function of the Streptozotocin-Induced Diabetic Mice?. Journal of Nutrition and Metabolism،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1183975
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yaghoubi, Atefe…[et al.]. Do Insulin Replacement and Omega3 Protect the Male Reproductive Function of the Streptozotocin-Induced Diabetic Mice?. Journal of Nutrition and Metabolism No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1183975
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yaghoubi, Atefe& Shahedi, Abbas& Akbari, Hakime& Nematollahi-Mahani, Seyed Noureddin. Do Insulin Replacement and Omega3 Protect the Male Reproductive Function of the Streptozotocin-Induced Diabetic Mice?. Journal of Nutrition and Metabolism. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1183975
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1183975
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر