![](/images/graphics-bg.png)
Improving In Vivo Efficacy of Bioactive Molecules: An Overview of Potentially Antitumor Phytochemicals and Currently Available Lipid-Based Delivery Systems
المؤلفون المشاركون
Torres, Carlos
Mouhid, Lamia
Corzo-Martínez, Marta
Vázquez, Luis
Ramírez de Molina, Ana
Reglero, Guillermo
Fornari, Tiziana
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-34، 34ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-05-07
دولة النشر
مصر
عدد الصفحات
34
التخصصات الرئيسية
الملخص EN
Cancer is among the leading causes of morbidity and mortality worldwide.
Many of the chemotherapeutic agents used in cancer treatment exhibit cell toxicity and display teratogenic effect on nontumor cells.
Therefore, the search for alternative compounds which are effective against tumor cells but reduce toxicity against nontumor ones is of great importance in the progress or development of cancer treatments.
In this sense, scientific knowledge about relevant aspects of nutrition intimately involved in the development and progression of cancer progresses rapidly.
Phytochemicals, considered as bioactive ingredients present in plant products, have shown promising effects as potential therapeutic/preventive agents on cancer in several in vitro and in vivo assays.
However, despite their bioactive properties, phytochemicals are still not commonly used in clinical practice due to several reasons, mainly attributed to their poor bioavailability.
In this sense, new formulation strategies are proposed as carriers to improve their bioefficacy, highlighting the use of lipid-based delivery systems.
Here, we review the potential antitumoral activity of the bioactive compounds derived from plants and the current studies carried out in animal and human models.
Furthermore, their association with lipids as a formulation strategy to enhance their efficacy in vivo is also reported.
The development of high effective bioactive supplements for cancer treatment based on the improvement of their bioavailability goes through this association.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mouhid, Lamia& Corzo-Martínez, Marta& Torres, Carlos& Vázquez, Luis& Reglero, Guillermo& Fornari, Tiziana…[et al.]. 2017. Improving In Vivo Efficacy of Bioactive Molecules: An Overview of Potentially Antitumor Phytochemicals and Currently Available Lipid-Based Delivery Systems. Journal of Oncology،Vol. 2017, no. 2017, pp.1-34.
https://search.emarefa.net/detail/BIM-1184207
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mouhid, Lamia…[et al.]. Improving In Vivo Efficacy of Bioactive Molecules: An Overview of Potentially Antitumor Phytochemicals and Currently Available Lipid-Based Delivery Systems. Journal of Oncology No. 2017 (2017), pp.1-34.
https://search.emarefa.net/detail/BIM-1184207
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mouhid, Lamia& Corzo-Martínez, Marta& Torres, Carlos& Vázquez, Luis& Reglero, Guillermo& Fornari, Tiziana…[et al.]. Improving In Vivo Efficacy of Bioactive Molecules: An Overview of Potentially Antitumor Phytochemicals and Currently Available Lipid-Based Delivery Systems. Journal of Oncology. 2017. Vol. 2017, no. 2017, pp.1-34.
https://search.emarefa.net/detail/BIM-1184207
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1184207
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)