A Perspective Review on the Role of Nanomedicine in the Modulation of TNF-TNFR2 Axis in Breast Cancer Immunotherapy

المؤلفون المشاركون

Chen, Xin
Al-Hatamleh, Mohammad A. I.
Ahmad, Suhana
Boer, Jennifer C.
Lim, JitKang
Plebanski, Magdalena
Mohamud, Rohimah

المصدر

Journal of Oncology

العدد

المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-13، 13ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2019-05-23

دولة النشر

مصر

عدد الصفحات

13

التخصصات الرئيسية

الأمراض
الطب البشري

الملخص EN

In the past decade, nanomedicine research has provided us with highly useful agents (nanoparticles) delivering therapeutic drugs to target cancer cells.

The present review highlights nanomedicine applications for breast cancer immunotherapy.

Recent studies have suggested that tumour necrosis factor (TNF) and its receptor 2 (TNFR2) expressed on breast cancer cells have important functional consequences.

This cytokine/receptor interaction is also critical for promoting highly immune-suppressive phenotypes by regulatory T cells (Tregs).

This review generally provides a background for nanoparticles as potential drug delivery agents for immunomodulators and further discusses in depth the potential of TNF antagonists delivery to modulate TNF-TNFR2 interactions and inhibit breast cancer progression.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Al-Hatamleh, Mohammad A. I.& Ahmad, Suhana& Boer, Jennifer C.& Lim, JitKang& Chen, Xin& Plebanski, Magdalena…[et al.]. 2019. A Perspective Review on the Role of Nanomedicine in the Modulation of TNF-TNFR2 Axis in Breast Cancer Immunotherapy. Journal of Oncology،Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1184425

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Al-Hatamleh, Mohammad A. I.…[et al.]. A Perspective Review on the Role of Nanomedicine in the Modulation of TNF-TNFR2 Axis in Breast Cancer Immunotherapy. Journal of Oncology No. 2019 (2019), pp.1-13.
https://search.emarefa.net/detail/BIM-1184425

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Al-Hatamleh, Mohammad A. I.& Ahmad, Suhana& Boer, Jennifer C.& Lim, JitKang& Chen, Xin& Plebanski, Magdalena…[et al.]. A Perspective Review on the Role of Nanomedicine in the Modulation of TNF-TNFR2 Axis in Breast Cancer Immunotherapy. Journal of Oncology. 2019. Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1184425

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1184425