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A Perspective Review on the Role of Nanomedicine in the Modulation of TNF-TNFR2 Axis in Breast Cancer Immunotherapy
Joint Authors
Chen, Xin
Al-Hatamleh, Mohammad A. I.
Ahmad, Suhana
Boer, Jennifer C.
Lim, JitKang
Plebanski, Magdalena
Mohamud, Rohimah
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-05-23
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
In the past decade, nanomedicine research has provided us with highly useful agents (nanoparticles) delivering therapeutic drugs to target cancer cells.
The present review highlights nanomedicine applications for breast cancer immunotherapy.
Recent studies have suggested that tumour necrosis factor (TNF) and its receptor 2 (TNFR2) expressed on breast cancer cells have important functional consequences.
This cytokine/receptor interaction is also critical for promoting highly immune-suppressive phenotypes by regulatory T cells (Tregs).
This review generally provides a background for nanoparticles as potential drug delivery agents for immunomodulators and further discusses in depth the potential of TNF antagonists delivery to modulate TNF-TNFR2 interactions and inhibit breast cancer progression.
American Psychological Association (APA)
Al-Hatamleh, Mohammad A. I.& Ahmad, Suhana& Boer, Jennifer C.& Lim, JitKang& Chen, Xin& Plebanski, Magdalena…[et al.]. 2019. A Perspective Review on the Role of Nanomedicine in the Modulation of TNF-TNFR2 Axis in Breast Cancer Immunotherapy. Journal of Oncology،Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1184425
Modern Language Association (MLA)
Al-Hatamleh, Mohammad A. I.…[et al.]. A Perspective Review on the Role of Nanomedicine in the Modulation of TNF-TNFR2 Axis in Breast Cancer Immunotherapy. Journal of Oncology No. 2019 (2019), pp.1-13.
https://search.emarefa.net/detail/BIM-1184425
American Medical Association (AMA)
Al-Hatamleh, Mohammad A. I.& Ahmad, Suhana& Boer, Jennifer C.& Lim, JitKang& Chen, Xin& Plebanski, Magdalena…[et al.]. A Perspective Review on the Role of Nanomedicine in the Modulation of TNF-TNFR2 Axis in Breast Cancer Immunotherapy. Journal of Oncology. 2019. Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1184425
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1184425