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The Association of Oxidative Stress Status with Open-Angle Glaucoma and Exfoliation Glaucoma: A Systematic Review and Meta-Analysis
المؤلفون المشاركون
Sun, Xinghuai
Li, Shengjie
Cao, Wenjun
Tang, Binghua
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-01-15
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Purpose.
To systematically evaluate the associations between oxidative stress status and different types of glaucoma.
Design.
Systematic review and meta-analysis.
Methods.
We searched PubMed, EMBASE, and the Web of Science for randomized controlled trials written in the English language between January 1, 1990, and November 30, 2016.
A random effects model was used to estimate oxidative stress status along with weighted mean differences and 95% confidence intervals (CIs).
A funnel plot analysis and Egger’s test were performed to assess potential publication bias.
Main outcome measures.
Oxidative stress status was abnormal and different in patients with OAG (open-angle glaucoma) and EXG (exfoliation glaucoma).
Results.
Blood TAS (total antioxidant status) was lower in the OAG group than in the control group, with a mean difference of 0.580 mmol/L (p<0.0001, 95% CI = −0.668 to −0.492).
The aqueous humor SOD (superoxide dismutase), GPX (glutathione peroxidase), and CAT (catalase) levels were higher in the OAG group than in the control group, with mean differences of 17.989 U/mL (p<0.0001, 95% CI = 14.579–21.298), 12.441 U/mL (p<0.0001, 95% CI = 10.423–14.459), and 1.229 fmol/mL (p=0.042, 95% CI = 0.043–2.414), respectively.
Blood TAS was lower in the EXG group than in the control group, with a mean difference of 0.262 mmol/L (p<0.0001, 95% CI = −0.393 to −0.132).
However, there were no differences in blood TOS and aqueous humor TOS between the EXG group and the control group.
Conclusions.
This meta-analysis indicates that OAG patients had a lower TAS in the blood and higher levels of SOD, GPX, and CAT in the aqueous humor, while EXG patients only had a decreased TAS in the blood.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tang, Binghua& Li, Shengjie& Cao, Wenjun& Sun, Xinghuai. 2019. The Association of Oxidative Stress Status with Open-Angle Glaucoma and Exfoliation Glaucoma: A Systematic Review and Meta-Analysis. Journal of Ophthalmology،Vol. 2019, no. 2019, pp.1-14.
https://search.emarefa.net/detail/BIM-1185138
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tang, Binghua…[et al.]. The Association of Oxidative Stress Status with Open-Angle Glaucoma and Exfoliation Glaucoma: A Systematic Review and Meta-Analysis. Journal of Ophthalmology No. 2019 (2019), pp.1-14.
https://search.emarefa.net/detail/BIM-1185138
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tang, Binghua& Li, Shengjie& Cao, Wenjun& Sun, Xinghuai. The Association of Oxidative Stress Status with Open-Angle Glaucoma and Exfoliation Glaucoma: A Systematic Review and Meta-Analysis. Journal of Ophthalmology. 2019. Vol. 2019, no. 2019, pp.1-14.
https://search.emarefa.net/detail/BIM-1185138
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1185138
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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