![](/images/graphics-bg.png)
Everolimus-Eluting Biodegradable Abluminal Coating Stent versus Durable Conformal Coating Stent: Termination of the Inflammatory Response Associated with Neointimal Healing in a Porcine Coronary Model
المؤلفون المشاركون
Nakanishi, Chiaki
Mori, Masayuki
Yoshida, Shohei
Yokawa, Junichiro
Sakata, Kenji
Murai, Kota
Okada, Hirofumi
Shimojima, Masaya
Yoshioka, Kazuaki
Takuwa, Yoh
Yamagishi, Masakazu
Kawashiri, Masaaki
Hayashi, Kenshi
المصدر
Journal of Interventional Cardiology
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-04-27
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Objectives.
We evaluated the effect of the different carrier systems on early vascular response through histological analysis and scanning electron microscopy using a porcine model.
Background.
Although Synergy™ and Promus PREMIER™ share an identical stent material and drug elution (everolimus), they use different drug carrier systems: biodegradable abluminal coating polymer or durable conformal coating polymer, respectively.
However, data regarding the impact of the different coating systems on vessel healing are currently limited.
Methods.
Twelve Synergy™ and Promus PREMIER™ were implanted in 12 swine.
Histopathological analysis of the stented segments was performed on the 2nd and 14th days after implantation.
Morphometric analysis of the inflammation and intimal fibrin content was also performed.
Results.
On the 2nd day, neointimal thickness, percentage of neointimal area, and inflammatory and intimal fibrin content scores were not significantly different between the two groups.
On the 14th day, the inflammatory and intimal fibrin content scores were significantly lower in Synergy™ versus those observed in Promus PREMIER™.
In Synergy™, smooth muscle cells were found and the neointimal layers were smooth.
In contrast, inflammatory cells were observed surrounding the struts of Promus PREMIER™.
Conclusions.
These results demonstrate that termination of reactive inflammation is accelerated after abluminal coating stent versus implantation of conformal coating stent.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mori, Masayuki& Sakata, Kenji& Yokawa, Junichiro& Nakanishi, Chiaki& Murai, Kota& Okada, Hirofumi…[et al.]. 2020. Everolimus-Eluting Biodegradable Abluminal Coating Stent versus Durable Conformal Coating Stent: Termination of the Inflammatory Response Associated with Neointimal Healing in a Porcine Coronary Model. Journal of Interventional Cardiology،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1187758
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mori, Masayuki…[et al.]. Everolimus-Eluting Biodegradable Abluminal Coating Stent versus Durable Conformal Coating Stent: Termination of the Inflammatory Response Associated with Neointimal Healing in a Porcine Coronary Model. Journal of Interventional Cardiology No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1187758
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mori, Masayuki& Sakata, Kenji& Yokawa, Junichiro& Nakanishi, Chiaki& Murai, Kota& Okada, Hirofumi…[et al.]. Everolimus-Eluting Biodegradable Abluminal Coating Stent versus Durable Conformal Coating Stent: Termination of the Inflammatory Response Associated with Neointimal Healing in a Porcine Coronary Model. Journal of Interventional Cardiology. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1187758
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1187758
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)