Different Dietary Proportions of Fish Oil Regulate Inflammatory Factors but Do Not Change Intestinal Tight Junction ZO-1 Expression in Ethanol-Fed Rats
المؤلفون المشاركون
Yang, Suh-Ching
Chen, Ya-Ling
Chien, Yi-Wen
Peng, Hsiang-Chi
Chuang, Hsiao-Li
Wang, Hsiao-Yun
Pai, Man-Hui
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-12-13
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Sixty male Wistar rats were fed a control or an ethanol-containing diet in groups C or E.
The fat compositions were adjusted with 25% or 57% fish oil substituted for olive oil in groups CF25, CF57, EF25, and EF57.
Hepatic thiobarbituric acid-reactive substance (TBARS) levels, cytochrome P450 2E1 protein expression, and tumor necrosis factor- (TNF-) α, interleukin- (IL-) 1β, IL-6, and IL-10 levels, as well as intracellular adhesion molecule (ICAM)-1 levels were significantly elevated, whereas plasma adiponectin level was significantly reduced in group E (p<0.05).
Hepatic histopathological scores of fatty change and inflammation, in group E were significantly higher than those of group C (p<0.05).
Hepatic TBARS, plasma ICAM-1, and hepatic TNF-α, IL-1β, and IL-10 levels were significantly lower, and plasma adiponectin levels were significantly higher in groups EF25 and EF57 than those in group E (p<0.05).
The immunoreactive area of the intestinal tight junction protein, ZO-1, showed no change between groups C and E.
Only group CF57 displayed a significantly higher ZO-1 immunoreactive area compared to group C (p=0.0415).
25% or 57% fish oil substituted for dietary olive oil could prevent ethanol-induced liver damage in rats, but the mechanism might not be related to intestinal tight junction ZO-1 expression.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chien, Yi-Wen& Peng, Hsiang-Chi& Chen, Ya-Ling& Pai, Man-Hui& Wang, Hsiao-Yun& Chuang, Hsiao-Li…[et al.]. 2017. Different Dietary Proportions of Fish Oil Regulate Inflammatory Factors but Do Not Change Intestinal Tight Junction ZO-1 Expression in Ethanol-Fed Rats. Mediators of Inflammation،Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1188498
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chien, Yi-Wen…[et al.]. Different Dietary Proportions of Fish Oil Regulate Inflammatory Factors but Do Not Change Intestinal Tight Junction ZO-1 Expression in Ethanol-Fed Rats. Mediators of Inflammation No. 2017 (2017), pp.1-11.
https://search.emarefa.net/detail/BIM-1188498
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chien, Yi-Wen& Peng, Hsiang-Chi& Chen, Ya-Ling& Pai, Man-Hui& Wang, Hsiao-Yun& Chuang, Hsiao-Li…[et al.]. Different Dietary Proportions of Fish Oil Regulate Inflammatory Factors but Do Not Change Intestinal Tight Junction ZO-1 Expression in Ethanol-Fed Rats. Mediators of Inflammation. 2017. Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1188498
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1188498
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر