Correlation between Urine N-Terminal Telopeptide and Fourier Transform Infrared Spectroscopy Parameters: A Preliminary Study
المؤلفون المشاركون
Girardi, Federico P.
Hughes, Alexander P.
Okano, Ichiro
Salzmann, Stephan N.
Ortiz Miller, Courtney
Rentenberger, Colleen
Schadler, Paul
Sax, Oliver C.
Shue, Jennifer
Cammisa, Frank P.
Sama, Andrew A.
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-02-11
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
N-terminal telopeptide (NTX) is a bone resorption marker that is commonly referenced in clinical practice.
Bone remodeling is also associated with changes in mineral components.
Fourier transform infrared spectroscopy (FTIR) is utilized in the assessment of bone material properties and some parameters are reported to have associations with bone remodeling.
The aim of this cross-sectional study is to investigate the relationship between uNTX levels and FTIR parameters, utilizing prospectively collected study data for patients who underwent lumbar fusion surgery.
Bone specimens were taken from iliac crest (IC) and vertebrae (V).
Cortical (C) and trabecular (T) bones were separately analyzed.
22 patients (mean age 60.0 years (35.9–73.3), male : female 9 : 13) were included in the final analysis.
Women showed significantly higher uNTX levels (male : female, median [range] 21.0 [11.0–39.0] : 36.0 [15.0–74.0] nM·BCE/mM, p=0.033).
Among women, a significant positive correlation was observed between uNTX and mineral-to-matrix ratio in IC-C.
Among men, uNTX demonstrated significant negative correlation with collagen crosslinks (XLR: ratio of mature to immature collagen crosslinks) in IC-C, V-T, and V-C.
In addition, uNTX was positively correlated with acid phosphate substitution (HPO4, a parameter of new bone formation) in IC-C, IC-T, and V-C.
After age adjustment, HPO4 in IC-T and V-C among men showed significant positive associations with uNTX (IC-T: p=0.018, R2 = 0.544; V-C: p=0.007, R2 = 0.672).
We found associations between FTIR parameters and uNTX in men, but not in women.
The correlations between uNTX and FTIR parameters in men might suggest a better balance of bone breakdown (uNTX) and new bone formation (FTIR parameters: XLR, HPO4) than in women.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Okano, Ichiro& Salzmann, Stephan N.& Ortiz Miller, Courtney& Rentenberger, Colleen& Schadler, Paul& Sax, Oliver C.…[et al.]. 2020. Correlation between Urine N-Terminal Telopeptide and Fourier Transform Infrared Spectroscopy Parameters: A Preliminary Study. Journal of Osteoporosis،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1189936
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Okano, Ichiro…[et al.]. Correlation between Urine N-Terminal Telopeptide and Fourier Transform Infrared Spectroscopy Parameters: A Preliminary Study. Journal of Osteoporosis No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1189936
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Okano, Ichiro& Salzmann, Stephan N.& Ortiz Miller, Courtney& Rentenberger, Colleen& Schadler, Paul& Sax, Oliver C.…[et al.]. Correlation between Urine N-Terminal Telopeptide and Fourier Transform Infrared Spectroscopy Parameters: A Preliminary Study. Journal of Osteoporosis. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1189936
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1189936
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر