Description of CD8+ Regulatory T Lymphocytes and Their Specific Intervention in Graft-versus-Host and Infectious Diseases, Autoimmunity, and Cancer
المؤلفون المشاركون
López-Santiago, Rubén
Vela-Ojeda, Jorge
Moreno-Lafont, Martha
Vieyra-Lobato, Martha R.
Montiel-Cervantes, Laura
المصدر
Journal of Immunology Research
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-16، 16ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-08-05
دولة النشر
مصر
عدد الصفحات
16
التخصصات الرئيسية
الملخص EN
Gershon and Kondo described CD8+ Treg lymphocytes as the first ones with regulating activity due to their tolerance ability to foreign antigens and their capacity to inhibit the proliferation of other lymphocytes.
Regardless, CD8+ Treg lymphocytes have not been fully described—unlike CD4+ Treg lymphocytes—because of their low numbers in blood and the lack of specific and accurate population markers.
Still, these lymphocytes have been studied for the past 30 years, even after finding difficulties during investigations.
As a result, studies have identified markers that define their subpopulations.
This review is focused on the expression of cell membrane markers as CD25, CD122, CD103, CTLA-4, CD39, CD73, LAG-3, and FasL as well as soluble molecules such as FoxP3, IFN-γ, IL-10, TGF-β, IL-34, and IL-35, in addition to the lack of expression of cell activation markers such as CD28, CD127 CD45RC, and CD49d.
This work also underlines the importance of identifying some of these markers in infections with several pathogens, autoimmunity, cancer, and graft-versus-host disease as a strategy in their prevention, monitoring, and cure.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Vieyra-Lobato, Martha R.& Vela-Ojeda, Jorge& Montiel-Cervantes, Laura& López-Santiago, Rubén& Moreno-Lafont, Martha. 2018. Description of CD8+ Regulatory T Lymphocytes and Their Specific Intervention in Graft-versus-Host and Infectious Diseases, Autoimmunity, and Cancer. Journal of Immunology Research،Vol. 2018, no. 2018, pp.1-16.
https://search.emarefa.net/detail/BIM-1192197
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Vieyra-Lobato, Martha R.…[et al.]. Description of CD8+ Regulatory T Lymphocytes and Their Specific Intervention in Graft-versus-Host and Infectious Diseases, Autoimmunity, and Cancer. Journal of Immunology Research No. 2018 (2018), pp.1-16.
https://search.emarefa.net/detail/BIM-1192197
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Vieyra-Lobato, Martha R.& Vela-Ojeda, Jorge& Montiel-Cervantes, Laura& López-Santiago, Rubén& Moreno-Lafont, Martha. Description of CD8+ Regulatory T Lymphocytes and Their Specific Intervention in Graft-versus-Host and Infectious Diseases, Autoimmunity, and Cancer. Journal of Immunology Research. 2018. Vol. 2018, no. 2018, pp.1-16.
https://search.emarefa.net/detail/BIM-1192197
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1192197
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر