The Epidemiology of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in China
المؤلفون المشاركون
Hu, Sindy
Cheng, Bo
Yang, Shang-Chen
Zhang, Sheng-Zheng
Huang, Jin-wen
Zhang, Jing
Ji, Chao
المصدر
Journal of Immunology Research
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-02-11
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are life-threatening disease.
However, there are only few epidemiologic studies of SJS/TEN from China.
To analyze the clinical characteristics, causality, and outcome of treatment for SJS/TEN in China, we reviewed case reports of patients with SJS/TEN from the China National Knowledge Infrastructure (CNKI) and Wanfang database from 2006 to 2016 and patients with SJS/TEN who were admitted to the First Affiliated Hospital of Fujian Medical University during the same period.
There were 166 patients enrolled, including 70 SJS, 2 SJS/TEN overlap, and 94 TEN.
The most common offending drugs were antibiotics (29.5%) and anticonvulsants (24.1%).
Carbamazepine, allopurinol, and penicillins were the most common single offending drugs (17.5%, 9.6%, and 7.2%).
Chinese patent medicines accounted for 5.4%.
There were 76 (45.8%) patients receiving systemic steroid and intravenous immunoglobulin (IVIG) in combination therapy, especially for TEN (80.3%), and others were treated with systemic steroids alone.
Mortality rate of combination treatment comparing with steroid alone in TEN patients had no statistical significance.
In conclusion, carbamazepine and allopurinol were the leading causative drugs for SJS/TEN in China.
Combination of IVIG and steroids is a common treatment for TEN, but its efficacy in improving mortality needs further investigation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yang, Shang-Chen& Hu, Sindy& Zhang, Sheng-Zheng& Huang, Jin-wen& Zhang, Jing& Ji, Chao…[et al.]. 2018. The Epidemiology of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in China. Journal of Immunology Research،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1192301
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yang, Shang-Chen…[et al.]. The Epidemiology of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in China. Journal of Immunology Research No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1192301
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yang, Shang-Chen& Hu, Sindy& Zhang, Sheng-Zheng& Huang, Jin-wen& Zhang, Jing& Ji, Chao…[et al.]. The Epidemiology of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in China. Journal of Immunology Research. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1192301
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1192301
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر