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Interhemispheric Pathways Are Important for Motor Outcome in Individuals with Chronic and Severe Upper Limb Impairment Post Stroke
المؤلفون المشاركون
Boyd, Lara A.
Peters, Sue
Hayward, Kathryn S.
Mang, Cameron S.
Neva, Jason L.
Wadden, Katie P.
Ferris, Jennifer K.
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-11-16
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Background.
Severity of arm impairment alone does not explain motor outcomes in people with severe impairment post stroke.
Objective.
Define the contribution of brain biomarkers to upper limb motor outcomes in people with severe arm impairment post stroke.
Methods.
Paretic arm impairment (Fugl-Meyer upper limb, FM-UL) and function (Wolf Motor Function Test rate, WMFT-rate) were measured in 15 individuals with severe (FM-UL ≤ 30/66) and 14 with mild–moderate (FM-UL > 40/66) impairment.
Transcranial magnetic stimulation and diffusion weight imaging indexed structure and function of the corticospinal tract and corpus callosum.
Separate models of the relationship between possible biomarkers and motor outcomes at a single chronic (≥6 months) time point post stroke were performed.
Results.
Age (ΔR20.365, p=0.017) and ipsilesional-transcallosal inhibition (ΔR20.182, p=0.048) explained a 54.7% (p=0.009) variance in paretic WMFT-rate.
Prefrontal corpus callous fractional anisotropy (PF-CC FA) alone explained 49.3% (p=0.007) variance in FM-UL outcome.
The same models did not explain significant variance in mild–moderate stroke.
In the severe group, k-means cluster analysis of PF-CC FA distinguished two subgroups, separated by a clinically meaningful and significant difference in motor impairment (p=0.049) and function (p=0.006) outcomes.
Conclusion.
Corpus callosum function and structure were identified as possible biomarkers of motor outcome in people with chronic and severe arm impairment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hayward, Kathryn S.& Neva, Jason L.& Mang, Cameron S.& Peters, Sue& Wadden, Katie P.& Ferris, Jennifer K.…[et al.]. 2017. Interhemispheric Pathways Are Important for Motor Outcome in Individuals with Chronic and Severe Upper Limb Impairment Post Stroke. Neural Plasticity،Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1193005
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hayward, Kathryn S.…[et al.]. Interhemispheric Pathways Are Important for Motor Outcome in Individuals with Chronic and Severe Upper Limb Impairment Post Stroke. Neural Plasticity No. 2017 (2017), pp.1-12.
https://search.emarefa.net/detail/BIM-1193005
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hayward, Kathryn S.& Neva, Jason L.& Mang, Cameron S.& Peters, Sue& Wadden, Katie P.& Ferris, Jennifer K.…[et al.]. Interhemispheric Pathways Are Important for Motor Outcome in Individuals with Chronic and Severe Upper Limb Impairment Post Stroke. Neural Plasticity. 2017. Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1193005
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1193005
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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