![](/images/graphics-bg.png)
Evaluation of the Hair Cell Regeneration in Zebrafish Larvae by Measuring and Quantifying the Startle Responses
المؤلفون المشاركون
Wang, Changquan
Zhong, Zhenmin
Sun, Peng
Zhong, Hanbing
Li, Hongzhe
Chen, Fangyi
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-01-29
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
The zebrafish has become an established model organism for the study of hearing and balance systems in the past two decades.
The classical approach to examine hair cells is to use dye to conduct selective staining, which shows the number and morphology of hair cells but does not reveal their function.
Startle response is a behavior closely related to the auditory function of hair cells; therefore it can be used to measure the function of hair cells.
In this study, we developed a device to measure the startle response of zebrafish larvae.
By applying various levels of stimulus, it showed that the system can discern a 10 dB difference.
The hair cell in zebrafish can regenerate after damage due to noise exposure or drug treatment.
With this device, we measured the startle response of zebrafish larvae during and after drug treatment.
The results show a similar trend to the classical hair cell staining method.
The startle response was reduced with drug treatment and recovered after removal of the drug.
Together it demonstrated the capability of this behavioral assay in evaluating the hair cell functions of fish larvae and its potential as a high-throughput screening tool for auditory-related gene and drug discovery.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Changquan& Zhong, Zhenmin& Sun, Peng& Zhong, Hanbing& Li, Hongzhe& Chen, Fangyi. 2017. Evaluation of the Hair Cell Regeneration in Zebrafish Larvae by Measuring and Quantifying the Startle Responses. Neural Plasticity،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1193254
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Changquan…[et al.]. Evaluation of the Hair Cell Regeneration in Zebrafish Larvae by Measuring and Quantifying the Startle Responses. Neural Plasticity No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1193254
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Changquan& Zhong, Zhenmin& Sun, Peng& Zhong, Hanbing& Li, Hongzhe& Chen, Fangyi. Evaluation of the Hair Cell Regeneration in Zebrafish Larvae by Measuring and Quantifying the Startle Responses. Neural Plasticity. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1193254
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1193254
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)