Altered Brain Functional Activity in Infants with Congenital Bilateral Severe Sensorineural Hearing Loss: A Resting-State Functional MRI Study under Sedation

المؤلفون المشاركون

Xia, Shuang
Song, TianBin
Che, Jing
Li, Qiang
Chai, Chao
Zheng, Meizhu
Shen, Wen

المصدر

Neural Plasticity

العدد

المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-8، 8ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2017-02-01

دولة النشر

مصر

عدد الصفحات

8

التخصصات الرئيسية

الأحياء
الطب البشري

الملخص EN

Early hearing deprivation could affect the development of auditory, language, and vision ability.

Insufficient or no stimulation of the auditory cortex during the sensitive periods of plasticity could affect the function of hearing, language, and vision development.

Twenty-three infants with congenital severe sensorineural hearing loss (CSSHL) and 17 age and sex matched normal hearing subjects were recruited.

The amplitude of low frequency fluctuations (ALFF) and regional homogeneity (ReHo) of the auditory, language, and vision related brain areas were compared between deaf infants and normal subjects.

Compared with normal hearing subjects, decreased ALFF and ReHo were observed in auditory and language-related cortex.

Increased ALFF and ReHo were observed in vision related cortex, which suggest that hearing and language function were impaired and vision function was enhanced due to the loss of hearing.

ALFF of left Brodmann area 45 (BA45) was negatively correlated with deaf duration in infants with CSSHL.

ALFF of right BA39 was positively correlated with deaf duration in infants with CSSHL.

In conclusion, ALFF and ReHo can reflect the abnormal brain function in language, auditory, and visual information processing in infants with CSSHL.

This demonstrates that the development of auditory, language, and vision processing function has been affected by congenital severe sensorineural hearing loss before 4 years of age.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Xia, Shuang& Song, TianBin& Che, Jing& Li, Qiang& Chai, Chao& Zheng, Meizhu…[et al.]. 2017. Altered Brain Functional Activity in Infants with Congenital Bilateral Severe Sensorineural Hearing Loss: A Resting-State Functional MRI Study under Sedation. Neural Plasticity،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1193328

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Xia, Shuang…[et al.]. Altered Brain Functional Activity in Infants with Congenital Bilateral Severe Sensorineural Hearing Loss: A Resting-State Functional MRI Study under Sedation. Neural Plasticity No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1193328

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Xia, Shuang& Song, TianBin& Che, Jing& Li, Qiang& Chai, Chao& Zheng, Meizhu…[et al.]. Altered Brain Functional Activity in Infants with Congenital Bilateral Severe Sensorineural Hearing Loss: A Resting-State Functional MRI Study under Sedation. Neural Plasticity. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1193328

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1193328