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Concurrent Aerobic and Resistance Training Has Anti-Inflammatory Effects and Increases Both Plasma and Leukocyte Levels of IGF-1 in Late Middle-Aged Type 2 Diabetic Patients
المؤلفون المشاركون
Vallorani, Luciana
Gioacchini, Anna Maria
Casadei, Lucia
Piccoli, Giovanni
Stocchi, Vilberto
Agostini, Deborah
Lucertini, Francesco
Annibalini, Giosuè
Passalia, Annunziata
Del Sal, Marta
Andreani, Mauro
Federici, Ario
Barbieri, Elena
Guescini, Michele
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-06-21
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Type 2 diabetes (T2D) is an age-related chronic disease associated with metabolic dysregulation, chronic inflammation, and activation of peripheral blood mononuclear cells (PBMC).
The aim of this study was to assess the effects of a concurrent exercise training program on inflammatory status and metabolic parameters of T2D patients.
Sixteen male patients (age range 55–70) were randomly assigned to an intervention group (n=8), which underwent a concurrent aerobic and resistance training program (3 times a week; 16 weeks), or to a control group, which followed physicians’ usual diabetes care advices.
Training intervention significantly improved patients’ body composition, blood pressure, total cholesterol, and overall fitness level.
After training, plasma levels of adipokines leptin (−33.9%) and RBP4 (−21.3%), and proinflammatory markers IL-6 (−25.3%), TNF-α (−19.8%) and MCP-1 (−15.3%) decreased, whereas anabolic hormone IGF-1 level increased (+16.4%).
All improvements were significantly greater than those of control patients.
Plasma proteomic profile of exercised patients showed a reduction of immunoglobulin K light chain and fibrinogen as well.
Training also induced a modulation of IL-6, IGF-1, and IGFBP-3 mRNAs in the PBMCs.
These findings confirm that concurrent aerobic and resistance training improves T2D-related metabolic abnormalities and has the potential to reduce the deleterious health effects of diabetes-related inflammation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Annibalini, Giosuè& Lucertini, Francesco& Agostini, Deborah& Vallorani, Luciana& Gioacchini, Anna Maria& Barbieri, Elena…[et al.]. 2017. Concurrent Aerobic and Resistance Training Has Anti-Inflammatory Effects and Increases Both Plasma and Leukocyte Levels of IGF-1 in Late Middle-Aged Type 2 Diabetic Patients. Oxidative Medicine and Cellular Longevity،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1194484
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Annibalini, Giosuè…[et al.]. Concurrent Aerobic and Resistance Training Has Anti-Inflammatory Effects and Increases Both Plasma and Leukocyte Levels of IGF-1 in Late Middle-Aged Type 2 Diabetic Patients. Oxidative Medicine and Cellular Longevity No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1194484
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Annibalini, Giosuè& Lucertini, Francesco& Agostini, Deborah& Vallorani, Luciana& Gioacchini, Anna Maria& Barbieri, Elena…[et al.]. Concurrent Aerobic and Resistance Training Has Anti-Inflammatory Effects and Increases Both Plasma and Leukocyte Levels of IGF-1 in Late Middle-Aged Type 2 Diabetic Patients. Oxidative Medicine and Cellular Longevity. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1194484
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1194484
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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