Association of the Composite Inflammatory Biomarker GlycA, with Exercise-Induced Changes in Body Habitus in Men and Women with Prediabetes
المؤلفون المشاركون
Bartlett, David B.
Slentz, Cris A.
Connelly, Margery A.
Piner, Lucy W.
Willis, Leslie H.
Bateman, Lori A.
Granville, Esther O.
Bales, Connie W.
Huffman, Kim M.
Kraus, William E.
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-05-31
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
GlycA is a new composite measure of systemic inflammation and a predictor of many inflammatory diseases.
GlycA is the nuclear magnetic resonance spectroscopy-derived signal arising from glucosamine residues on acute-phase proteins.
This study aimed to evaluate how exercise-based lifestyle interventions modulate GlycA in persons at risk for type 2 diabetes.
GlycA, fitness, and body habitus were measured in 169 sedentary adults (45–75 years) with prediabetes randomly assigned to one of four six-month exercise-based lifestyle interventions.
Interventions included exercise prescription based on the amount (energy expenditure (kcal/kg weight/week (KKW)) and intensity (%VO2peak).
The groups were (1) low-amount/moderate-intensity (10KKW/50%) exercise; (2) high-amount/moderate-intensity (16KKW/50%) exercise; (3) high-amount/vigorous-intensity (16KKW/75%) exercise; and (4) a Clinical Lifestyle (combined diet plus low-amount/moderate-intensity exercise) intervention.
Six months of exercise training and/or diet-reduced GlycA (mean Δ: −6.8 ± 29.2 μmol/L; p=0.006) and increased VO2peak (mean Δ: 1.98 ± 2.6 mL/kg/min; p<0.001).
Further, visceral (mean Δ: −21.1 ± 36.6 cm2) and subcutaneous fat (mean Δ: −24.3 ± 41.0 cm2) were reduced, while liver density (mean Δ: +2.3 ± 6.5HU) increased, all p<0.001.
When including individuals in all four interventions, GlycA reductions were associated with reductions in visceral adiposity (p<0.03).
Exercise-based lifestyle interventions reduced GlycA concentrations through mechanisms related to exercise-induced modulations of visceral adiposity.
This trial is registered with Clinical Trial Registration Number NCT00962962.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bartlett, David B.& Slentz, Cris A.& Connelly, Margery A.& Piner, Lucy W.& Willis, Leslie H.& Bateman, Lori A.…[et al.]. 2017. Association of the Composite Inflammatory Biomarker GlycA, with Exercise-Induced Changes in Body Habitus in Men and Women with Prediabetes. Oxidative Medicine and Cellular Longevity،Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1194993
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bartlett, David B.…[et al.]. Association of the Composite Inflammatory Biomarker GlycA, with Exercise-Induced Changes in Body Habitus in Men and Women with Prediabetes. Oxidative Medicine and Cellular Longevity No. 2017 (2017), pp.1-12.
https://search.emarefa.net/detail/BIM-1194993
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bartlett, David B.& Slentz, Cris A.& Connelly, Margery A.& Piner, Lucy W.& Willis, Leslie H.& Bateman, Lori A.…[et al.]. Association of the Composite Inflammatory Biomarker GlycA, with Exercise-Induced Changes in Body Habitus in Men and Women with Prediabetes. Oxidative Medicine and Cellular Longevity. 2017. Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1194993
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1194993
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر