Gut Microbiota as a Prospective Therapeutic Target for Curcumin: A Review of Mutual Influence
المؤلف
المصدر
Journal of Nutrition and Metabolism
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-12-16
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Background.
Turmeric is a spice that has recently received much interest and has been widely used in Ayurvedic medicine.
Turmeric products are diarylheptanoids and have been characterized as safe.
They are termed as curcuminoids that consists essentially of three major compounds: curcumin, demethoxycurcumin, and bisdemethoxycurcumin.
Curcumin is a lipophilic polyphenol that has poor systemic bioavailability and suffers from biotransformation by human intestinal microflora to yield different metabolites that are easily conjugated to glucuronides and sulfate O-conjugated derivatives.
Recently, an increasing number of studies have indicated that dysbiosis is linked with many metabolic diseases, though gut microbiota could be a novel potential therapeutic target.
Scope and Approach.
Thus, it is suspected that curcumin and its derivatives exert direct regulative effects on the gut microbiota which could explain the paradox between curcumin’s poor systemic bioavailability and its widely reported pharmacological activities.
Key Findings and Conclusions.
This article summarizes a range of studies that highlight the interaction between curcumin and gut microbiota and considers opportunities for microbiome-targeting therapies using turmeric extract.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zam, Wissam. 2018. Gut Microbiota as a Prospective Therapeutic Target for Curcumin: A Review of Mutual Influence. Journal of Nutrition and Metabolism،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1195355
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zam, Wissam. Gut Microbiota as a Prospective Therapeutic Target for Curcumin: A Review of Mutual Influence. Journal of Nutrition and Metabolism No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1195355
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zam, Wissam. Gut Microbiota as a Prospective Therapeutic Target for Curcumin: A Review of Mutual Influence. Journal of Nutrition and Metabolism. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1195355
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1195355
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر