Inhibition of Intestinal Cellular Glucose Uptake by Phenolics Extracted from Whole Wheat Grown at Different Locations
المؤلفون المشاركون
Eck, Peter
Shamloo, Maryam
Jones, Peter J. H.
المصدر
Journal of Nutrition and Metabolism
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-03-18
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Whole grain consumption is associated with reduced risk of type 2 diabetes, and the underlying mechanism might be related to the actions of polyphenols.
Dietary polyphenols contribute to low glycemic indices through inhibition of intestinal glucose transport proteins.
This study has two objectives: (1) to evaluate how the contents of phenolic acids in wheat vary by genetic background and growth condition and (2) to evaluate how these changes translate into physiologic relevance by investigating cellular glucose transporter inhibitions.
Phenolic acids were extracted from wheat varieties grown at different locations over two crop years.
The degree of inhibition of glucose uptake into human Caco-2E cells was determined.
Free and bound phenolic acid extracts of all wheat genotypes inhibited glucose uptake.
Degree of glucose uptake inhibitions positively correlated with the contents of free and bound phenolic acids, and the correlation coefficients were R2=0.91 and R2=0.89, respectively.
Genotype and environment influenced the content of free and bound phenolic acids which linearly translated to the degree of glucose uptake inhibition in a model of intestinal absorption (P<0.05).
Results of this work mechanistically support the hypothesis that dietary phenols positively influence the glycemic index and therefore the health properties of whole grain consumption.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Shamloo, Maryam& Jones, Peter J. H.& Eck, Peter. 2018. Inhibition of Intestinal Cellular Glucose Uptake by Phenolics Extracted from Whole Wheat Grown at Different Locations. Journal of Nutrition and Metabolism،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1195404
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Shamloo, Maryam…[et al.]. Inhibition of Intestinal Cellular Glucose Uptake by Phenolics Extracted from Whole Wheat Grown at Different Locations. Journal of Nutrition and Metabolism No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1195404
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Shamloo, Maryam& Jones, Peter J. H.& Eck, Peter. Inhibition of Intestinal Cellular Glucose Uptake by Phenolics Extracted from Whole Wheat Grown at Different Locations. Journal of Nutrition and Metabolism. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1195404
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1195404
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر