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Antigenotoxic Properties of Agaricus blazei against Hydrogen Peroxide in Human Peripheral Blood Cells
المؤلفون المشاركون
Bajić, Vladan
Živković, Lada
Žukovec Topalović, Dijana
Čabarkapa, Andrea
Spremo-Potparević, Biljana
Borozan, Sunčica
Ciptasari, Ummi
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-02-21
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
The ability of Agaricus blazei mushroom in its dried and powdered mycelial form was evaluated for its antigenotoxic properties for the first time.
Antigenotoxic effects in human peripheral blood cells against H2O2-induced DNA damage were examined in pretreatment and posttreatment protocol by comet assay.
The results showed better antigenotoxic properties of Agaricus blazei on the interventional level, respectively, after treatment.
Agaricus blazei in concentration of 250 μg/mL after treatment was most efficient in regard to its action against DNA damage.
The evaluation of repair kinetics showed decrease in H2O2 induced DNA damage 15 min after the application of A.
blazei, reaching the maximum potency after 30 min.
Analysis of antioxidant properties of Agaricus blazei revealed strong OH• scavenging properties and moderate reducing power, while its DPPH scavenging ability was weak.
In regard to our findings, we can conclude that our preliminary results demonstrated antigenotoxic properties of Agaricus blazei and its strong OH• scavenging ability.
Mechanisms underlying its properties should be further evaluated in in vivo studies.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Živković, Lada& Borozan, Sunčica& Čabarkapa, Andrea& Žukovec Topalović, Dijana& Ciptasari, Ummi& Bajić, Vladan…[et al.]. 2017. Antigenotoxic Properties of Agaricus blazei against Hydrogen Peroxide in Human Peripheral Blood Cells. Oxidative Medicine and Cellular Longevity،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1196272
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Živković, Lada…[et al.]. Antigenotoxic Properties of Agaricus blazei against Hydrogen Peroxide in Human Peripheral Blood Cells. Oxidative Medicine and Cellular Longevity No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1196272
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Živković, Lada& Borozan, Sunčica& Čabarkapa, Andrea& Žukovec Topalović, Dijana& Ciptasari, Ummi& Bajić, Vladan…[et al.]. Antigenotoxic Properties of Agaricus blazei against Hydrogen Peroxide in Human Peripheral Blood Cells. Oxidative Medicine and Cellular Longevity. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1196272
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1196272
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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