Cytoprotective Mechanisms Mediated by Polyphenols from Chilean Native Berries against Free Radical-Induced Damage on AGS Cells
المؤلفون المشاركون
López-Alarcón, Camilo
Felipe, Avila
Theoduloz, Cristina
Dorta, Eva
Schmeda-Hirschmann, Guillermo
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-05-02
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
The prevalence of cytoprotective mechanisms induced by polyphenols such as activation of intracellular antioxidant responses (ICM) and direct free radical scavenging was investigated in native Chilean species of strawberries, raspberries, and currants.
Human gastric epithelial cells were co- and preincubated with polyphenolic-enriched extracts (PEEs) from Chilean raspberries (Rubus geoides), strawberries (Fragaria chiloensis ssp.
chiloensis f.
chiloensis), and currants (Ribes magellanicum) and challenged with peroxyl and hydroxyl radicals.
Cellular protection was determined in terms of cell viability, glyoxalase I and glutathione s-transferases activities, and carboxymethyl lysine (CML) and malondialdehyde levels.
Our results indicate that cytoprotection induced by ICM was the prevalent mechanism for Rubus geoides and F.
chiloensis.
This agreed with increased levels of glyoxalase I and glutathione S-transferase activities in cells preincubated with PEEs.
ORAC index indicated that F.
chiloensis was the most efficient peroxyl radical scavenger.
Moreover, ICM mediated by F.
chiloensis was effective in protecting cells from CML accumulation in contrast to the protective effects induced by free radical scavenging.
Our results indicate that although both polyphenol-mediated mechanisms can exert protective effects, ICM was the most prevalent in AGS cells.
These results suggest a potential use of these native berries as functional food.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Felipe, Avila& Theoduloz, Cristina& López-Alarcón, Camilo& Dorta, Eva& Schmeda-Hirschmann, Guillermo. 2017. Cytoprotective Mechanisms Mediated by Polyphenols from Chilean Native Berries against Free Radical-Induced Damage on AGS Cells. Oxidative Medicine and Cellular Longevity،Vol. 2017, no. 2017, pp.1-13.
https://search.emarefa.net/detail/BIM-1196737
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Felipe, Avila…[et al.]. Cytoprotective Mechanisms Mediated by Polyphenols from Chilean Native Berries against Free Radical-Induced Damage on AGS Cells. Oxidative Medicine and Cellular Longevity No. 2017 (2017), pp.1-13.
https://search.emarefa.net/detail/BIM-1196737
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Felipe, Avila& Theoduloz, Cristina& López-Alarcón, Camilo& Dorta, Eva& Schmeda-Hirschmann, Guillermo. Cytoprotective Mechanisms Mediated by Polyphenols from Chilean Native Berries against Free Radical-Induced Damage on AGS Cells. Oxidative Medicine and Cellular Longevity. 2017. Vol. 2017, no. 2017, pp.1-13.
https://search.emarefa.net/detail/BIM-1196737
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1196737
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر