Is the Retinal Vasculature Related to β-Peripapillary Atrophy in Nonpathological High Myopia? An Optical Coherence Tomography Angiography Study in Chinese Adults

المؤلفون المشاركون

Wang, Yanling
Sun, Jiao
Wang, Jialin
You, Ran

المصدر

Journal of Ophthalmology

العدد

المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-8، 8ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2018-09-30

دولة النشر

مصر

عدد الصفحات

8

التخصصات الرئيسية

الطب البشري

الملخص EN

Purpose.

The association between β-peripapillary atrophy and the retinal vasculature in nonpathological high myopia is unclear.

The aim of this study is to investigate whether β-peripapillary atrophy contribute to the changes of the retinal vasculature using optical coherence tomography angiography.

Methods.

In a cross-sectional study, one hundred and thirty eyes with nonpathological high myopia were included.

β-peripapillary atrophy was analysed using Image J software based on fundus photographs.

A 3.0 × 3.0 mm2 grid and a 4.5 × 4.5 mm2 grid were used to scan parafoveal and peripapillary regions using optical coherence tomography angiography, respectively.

Vessel density and fractal dimensions of the retina and foveal avascular zone were analysed and quantified using en face projection images.

Correlations between the vascular density, foveal avascular zone, and β-peripapillary atrophy were determined.

Results.

Using multivariate analysis, β-peripapillary atrophy was negatively correlated with the vessel density in radial peripapillary capillaries (p=0.002) even after adjusting for other variables.

This relationship was also confirmed in the macula (superficial retinal plexus: p<0.05; deep retinal plexus: p<0.05).

The vessel densities in the nasal and inferior sectors were more strongly correlated with β-peripapillary atrophy.

Conclusions.

There was a negative correlation between β-peripapillary atrophy and the retinal vasculature in highly myopic eyes, especially in radial peripapillary capillaries and deep retinal plexus.

β-peripapillary atrophy can be visualized and is a convenient structural feature that can benefit the early diagnosis and detection of chorioretinal atrophy in high myopia.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Sun, Jiao& Wang, Jialin& You, Ran& Wang, Yanling. 2018. Is the Retinal Vasculature Related to β-Peripapillary Atrophy in Nonpathological High Myopia? An Optical Coherence Tomography Angiography Study in Chinese Adults. Journal of Ophthalmology،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1196938

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Sun, Jiao…[et al.]. Is the Retinal Vasculature Related to β-Peripapillary Atrophy in Nonpathological High Myopia? An Optical Coherence Tomography Angiography Study in Chinese Adults. Journal of Ophthalmology No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1196938

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Sun, Jiao& Wang, Jialin& You, Ran& Wang, Yanling. Is the Retinal Vasculature Related to β-Peripapillary Atrophy in Nonpathological High Myopia? An Optical Coherence Tomography Angiography Study in Chinese Adults. Journal of Ophthalmology. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1196938

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1196938