Is the Retinal Vasculature Related to β-Peripapillary Atrophy in Nonpathological High Myopia? An Optical Coherence Tomography Angiography Study in Chinese Adults
Joint Authors
Wang, Yanling
Sun, Jiao
Wang, Jialin
You, Ran
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-30
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Purpose.
The association between β-peripapillary atrophy and the retinal vasculature in nonpathological high myopia is unclear.
The aim of this study is to investigate whether β-peripapillary atrophy contribute to the changes of the retinal vasculature using optical coherence tomography angiography.
Methods.
In a cross-sectional study, one hundred and thirty eyes with nonpathological high myopia were included.
β-peripapillary atrophy was analysed using Image J software based on fundus photographs.
A 3.0 × 3.0 mm2 grid and a 4.5 × 4.5 mm2 grid were used to scan parafoveal and peripapillary regions using optical coherence tomography angiography, respectively.
Vessel density and fractal dimensions of the retina and foveal avascular zone were analysed and quantified using en face projection images.
Correlations between the vascular density, foveal avascular zone, and β-peripapillary atrophy were determined.
Results.
Using multivariate analysis, β-peripapillary atrophy was negatively correlated with the vessel density in radial peripapillary capillaries (p=0.002) even after adjusting for other variables.
This relationship was also confirmed in the macula (superficial retinal plexus: p<0.05; deep retinal plexus: p<0.05).
The vessel densities in the nasal and inferior sectors were more strongly correlated with β-peripapillary atrophy.
Conclusions.
There was a negative correlation between β-peripapillary atrophy and the retinal vasculature in highly myopic eyes, especially in radial peripapillary capillaries and deep retinal plexus.
β-peripapillary atrophy can be visualized and is a convenient structural feature that can benefit the early diagnosis and detection of chorioretinal atrophy in high myopia.
American Psychological Association (APA)
Sun, Jiao& Wang, Jialin& You, Ran& Wang, Yanling. 2018. Is the Retinal Vasculature Related to β-Peripapillary Atrophy in Nonpathological High Myopia? An Optical Coherence Tomography Angiography Study in Chinese Adults. Journal of Ophthalmology،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1196938
Modern Language Association (MLA)
Sun, Jiao…[et al.]. Is the Retinal Vasculature Related to β-Peripapillary Atrophy in Nonpathological High Myopia? An Optical Coherence Tomography Angiography Study in Chinese Adults. Journal of Ophthalmology No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1196938
American Medical Association (AMA)
Sun, Jiao& Wang, Jialin& You, Ran& Wang, Yanling. Is the Retinal Vasculature Related to β-Peripapillary Atrophy in Nonpathological High Myopia? An Optical Coherence Tomography Angiography Study in Chinese Adults. Journal of Ophthalmology. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1196938
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1196938