Intravenous Lidocaine: Old-School Drug, New Purpose—Reduction of Intractable Pain in Patients with Chemotherapy Induced Peripheral Neuropathy
المؤلفون المشاركون
van der Wal, Selina
Vissers, Kris
Heuvel, Sandra A. S. van den
Smedes, Lotte A.
Radema, Sandra A.
Alfen, Nens van
Steegers, Monique A. H.
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-03-28
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background.
Treatment of intractable pain due to chemotherapy induced peripheral neuropathy (CIPN) is a challenge.
Intravenous (iv) lidocaine has shown to be a treatment option for neuropathic pain of different etiologies.
Methods.
Lidocaine (1.5 mg/kg in 10 minutes followed by 1.5 mg/kg/h over 5 hours) was administered in nine patients with CIPN, and analgesic effect was evaluated during infusion and after discharge.
The immediate effect of lidocaine on pressure pain thresholds (PPT) and the extent of the stocking and glove distribution of sensory abnormalities (cold and pinprick) were assessed.
Results.
Lidocaine had a significant direct analgesic effect in 8 out of 9 patients (P=0.01) with a pain intensity difference of >30%.
Pain reduction persisted in 5 patients for an average of 23 days.
Lidocaine did not influence mean PPT, but there was a tendency that the extent of sensory abnormalities decreased after lidocaine.
Conclusion.
Iv lidocaine has direct analgesic effect in CIPN with a moderate long-term effect and seems to influence the area of cold and pinprick perception.
Additional research is needed, using a control group and larger sample sizes to confirm these results.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Heuvel, Sandra A. S. van den& van der Wal, Selina& Smedes, Lotte A.& Radema, Sandra A.& Alfen, Nens van& Vissers, Kris…[et al.]. 2017. Intravenous Lidocaine: Old-School Drug, New Purpose—Reduction of Intractable Pain in Patients with Chemotherapy Induced Peripheral Neuropathy. Pain Research and Management،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1197513
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Heuvel, Sandra A. S. van den…[et al.]. Intravenous Lidocaine: Old-School Drug, New Purpose—Reduction of Intractable Pain in Patients with Chemotherapy Induced Peripheral Neuropathy. Pain Research and Management No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1197513
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Heuvel, Sandra A. S. van den& van der Wal, Selina& Smedes, Lotte A.& Radema, Sandra A.& Alfen, Nens van& Vissers, Kris…[et al.]. Intravenous Lidocaine: Old-School Drug, New Purpose—Reduction of Intractable Pain in Patients with Chemotherapy Induced Peripheral Neuropathy. Pain Research and Management. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1197513
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1197513
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر