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Multimodal Approach of Pulmonary Artery Intimal Sarcoma: A Single-Institution Experience
المؤلفون المشاركون
Morbini, Patrizia
D'Armini, Andrea Maria
Klersy, Catherine
Secondino, S.
Grazioli, V.
Valentino, F.
Pin, M.
Pagani, A.
Sciortino, A.
Callegari, M. G.
Dore, R.
Paulli, M.
Pedrazzoli, Paolo
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-08-20
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Introduction.
Pulmonary artery sarcoma (PAS) is a rare tumor, whose therapeutic approach is mainly based on surgery, either pneumonectomy or pulmonary endarterectomy (PEA).
The prognosis reported in published series is very poor, with survival of 1.5 months without any kind of treatment.
Patients and Methods.
From January 2010 to January 2016, 1027 patients were referred to our hospital for symptoms of acute or chronic pulmonary thromboembolic disease.
Twelve patients having a confirmed diagnosis of PAS underwent PEA.
Median age was 64.5 years.
Most patients had a long history of symptoms, having a median time of 7.5 months from onset of symptoms to surgery.
Results.
Following PEA and cardiopulmonary rehabilitation, 10 patients received conventional chemotherapy with doxorubicin and ifosfamide, starting at a median of 42 days from surgery.
Four patients also received radiotherapy.
Four patients have died due to disease progression, while 7 are still alive, with 5 being disease-free at 4–55+ months from diagnosis.
Conclusions.
In patients with PAS, a multimodal approach including PEA, CT, and RT is feasible but it should be evaluated individually, according to the tumor extension and the patient’s clinical condition.
Apart from improving quality of life mainly by reducing or delaying symptoms due to PH, it may improve life expectancy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Secondino, S.& Grazioli, V.& Valentino, F.& Pin, M.& Pagani, A.& Sciortino, A.…[et al.]. 2017. Multimodal Approach of Pulmonary Artery Intimal Sarcoma: A Single-Institution Experience. Complexity،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1197745
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Secondino, S.…[et al.]. Multimodal Approach of Pulmonary Artery Intimal Sarcoma: A Single-Institution Experience. Complexity No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1197745
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Secondino, S.& Grazioli, V.& Valentino, F.& Pin, M.& Pagani, A.& Sciortino, A.…[et al.]. Multimodal Approach of Pulmonary Artery Intimal Sarcoma: A Single-Institution Experience. Complexity. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1197745
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1197745
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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