![](/images/graphics-bg.png)
Different Brain Connectivity between Responders and Nonresponders to Dual-Mode Noninvasive Brain Stimulation over Bilateral Primary Motor Cortices in Stroke Patients
المؤلفون المشاركون
Lee, Jungsoo
Lee, Ahee
Kim, Heegoo
Shin, Mina
Yun, Sang Moon
Jung, Youngjin
Chang, Won Hyuk
Kim, Yun-Hee
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-04-07
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Noninvasive brain stimulation (NBS), such as repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS), has been used in stroke patients with motor impairment.
NBS can help recovery from brain damage by modulating cortical excitability.
However, the efficacy of NBS varies among individuals.
To obtain insights of responsiveness to the efficacy of NBS, we investigated characteristic changes of the motor network in responders and nonresponders of NBS over the primary motor cortex (M1).
A total of 21 patients with subacute stroke (13 males, mean age 59.6±11.5 years) received NBS in the same manner: 1 Hz rTMS on the contralesional M1 and anodal tDCS on the ipsilesional M1.
Participants were classified into responders and nonresponders based on the functional improvement of the affected upper extremity after applying NBS.
Twelve age-matched healthy controls (8 males, mean age 56.1±14.3 years) were also recruited.
Motor networks were constructed using resting-state functional magnetic resonance imaging.
M1 intrahemispheric connectivity, interhemispheric connectivity, and network efficiency were measured to investigate differences in network characteristics between groups.
The motor network characteristics were found to differ between both groups.
Specifically, M1 intrahemispheric connectivity in responders showed a noticeable imbalance between affected and unaffected hemispheres, which was markedly restored after NBS.
The responders also showed greater interhemispheric connectivity and higher efficiency of the motor network than the nonresponders.
These results may provide insight on patient-specific NBS treatment based on the brain network characteristics in neurorehabilitation of patients with stroke.
This trial is registered with trial registration number NCT03390192.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lee, Jungsoo& Lee, Ahee& Kim, Heegoo& Shin, Mina& Yun, Sang Moon& Jung, Youngjin…[et al.]. 2019. Different Brain Connectivity between Responders and Nonresponders to Dual-Mode Noninvasive Brain Stimulation over Bilateral Primary Motor Cortices in Stroke Patients. Neural Plasticity،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1201185
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lee, Jungsoo…[et al.]. Different Brain Connectivity between Responders and Nonresponders to Dual-Mode Noninvasive Brain Stimulation over Bilateral Primary Motor Cortices in Stroke Patients. Neural Plasticity No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1201185
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lee, Jungsoo& Lee, Ahee& Kim, Heegoo& Shin, Mina& Yun, Sang Moon& Jung, Youngjin…[et al.]. Different Brain Connectivity between Responders and Nonresponders to Dual-Mode Noninvasive Brain Stimulation over Bilateral Primary Motor Cortices in Stroke Patients. Neural Plasticity. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1201185
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1201185
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)