Transcranial Magnetic Stimulation as a Potential Biomarker in Multiple Sclerosis: A Systematic Review with Recommendations for Future Research
المؤلفون المشاركون
Ploughman, Michelle
Wadden, Katie P.
Snow, Nicholas J.
Chaves, Arthur R.
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-22، 22ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-09-16
دولة النشر
مصر
عدد الصفحات
22
التخصصات الرئيسية
الملخص EN
Multiple sclerosis (MS) is a demyelinating disorder of the central nervous system.
Disease progression is variable and unpredictable, warranting the development of biomarkers of disease status.
Transcranial magnetic stimulation (TMS) is a noninvasive method used to study the human motor system, which has shown potential in MS research.
However, few reviews have summarized the use of TMS combined with clinical measures of MS and no work has comprehensively assessed study quality.
This review explored the viability of TMS as a biomarker in studies of MS examining disease severity, cognitive impairment, motor impairment, or fatigue.
Methodological quality and risk of bias were evaluated in studies meeting selection criteria.
After screening 1603 records, 30 were included for review.
All studies showed high risk of bias, attributed largely to issues surrounding sample size justification, experimenter blinding, and failure to account for key potential confounding variables.
Central motor conduction time and motor-evoked potentials were the most commonly used TMS techniques and showed relationships with disease severity, motor impairment, and fatigue.
Short-latency afferent inhibition was the only outcome related to cognitive impairment.
Although there is insufficient evidence for TMS in clinical assessments of MS, this review serves as a template to inform future research.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Snow, Nicholas J.& Wadden, Katie P.& Chaves, Arthur R.& Ploughman, Michelle. 2019. Transcranial Magnetic Stimulation as a Potential Biomarker in Multiple Sclerosis: A Systematic Review with Recommendations for Future Research. Neural Plasticity،Vol. 2019, no. 2019, pp.1-22.
https://search.emarefa.net/detail/BIM-1201522
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Snow, Nicholas J.…[et al.]. Transcranial Magnetic Stimulation as a Potential Biomarker in Multiple Sclerosis: A Systematic Review with Recommendations for Future Research. Neural Plasticity No. 2019 (2019), pp.1-22.
https://search.emarefa.net/detail/BIM-1201522
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Snow, Nicholas J.& Wadden, Katie P.& Chaves, Arthur R.& Ploughman, Michelle. Transcranial Magnetic Stimulation as a Potential Biomarker in Multiple Sclerosis: A Systematic Review with Recommendations for Future Research. Neural Plasticity. 2019. Vol. 2019, no. 2019, pp.1-22.
https://search.emarefa.net/detail/BIM-1201522
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1201522
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر