CD60b: Enriching Neural StemProgenitor Cells from Rat Development into Adulthood
المؤلفون المشاركون
Pimentel-Coelho, Pedro Moreno
Zaverucha-do-Valle, Camila
Santiago, Marcelo F.
Gubert, Fernanda
Furtado, Michelle
Mortari, Nicoli
Leão, Ana C. M.
Hayashi, Elize A.
Nobrega, Alberto
Mendez-Otero, Rosalia
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-16، 16ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-11-15
دولة النشر
مصر
عدد الصفحات
16
الملخص EN
CD60b antigens are highly expressed during development in the rat nervous system, while in the adult their expression is restricted to a few regions, including the subventricular zone (SVZ) around the lateral ventricles—a neurogenic niche in the adult brain.
For this reason, we investigated whether the expression of C60b is associated with neural stem/progenitor cells in the SVZ, from development into adulthood.
We performed in vitro and in vivo analyses of CD60b expression at different stages and identified the presence of these antigens in neural stem/progenitor cells.
We also observed that CD60b could be used to purify and enrich a population of neurosphere-forming cells from the developing and adult brain.
We showed that CD60b antigens (mainly corresponding to ganglioside 9-O-acetyl GD3, a well-known molecule expressed during central nervous system development and mainly associated with neuronal migration) are also present in less mature cells and could be used to identify and isolate neural stem/progenitor cells during development and in the adult brain.
A better understanding of molecules associated with neurogenesis may contribute not only to improve the knowledge about the physiology of the mammalian central nervous system, but also to find new treatments for regenerating tissue after disease or brain injury.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gubert, Fernanda& Zaverucha-do-Valle, Camila& Furtado, Michelle& Pimentel-Coelho, Pedro Moreno& Mortari, Nicoli& Leão, Ana C. M.…[et al.]. 2017. CD60b: Enriching Neural StemProgenitor Cells from Rat Development into Adulthood. Stem Cells International،Vol. 2017, no. 2017, pp.1-16.
https://search.emarefa.net/detail/BIM-1201823
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gubert, Fernanda…[et al.]. CD60b: Enriching Neural StemProgenitor Cells from Rat Development into Adulthood. Stem Cells International No. 2017 (2017), pp.1-16.
https://search.emarefa.net/detail/BIM-1201823
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gubert, Fernanda& Zaverucha-do-Valle, Camila& Furtado, Michelle& Pimentel-Coelho, Pedro Moreno& Mortari, Nicoli& Leão, Ana C. M.…[et al.]. CD60b: Enriching Neural StemProgenitor Cells from Rat Development into Adulthood. Stem Cells International. 2017. Vol. 2017, no. 2017, pp.1-16.
https://search.emarefa.net/detail/BIM-1201823
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1201823
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر