Literature-Based Enrichment Insights into Redox Control of Vascular Biology
المؤلفون المشاركون
Bajic, Vladimir
Isenovic, Esma R.
Essack, Magbubah
Salhi, Adil
Stanimirovic, Julijana
Tifratene, Faroug
Bin Raies, Arwa
Hungler, Arnaud
Uludag, Mahmut
Van Neste, Christophe
Trpkovic, Andreja
Bajic, Vladan P.
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-16، 16ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-05-16
دولة النشر
مصر
عدد الصفحات
16
التخصصات الرئيسية
الملخص EN
In cellular physiology and signaling, reactive oxygen species (ROS) play one of the most critical roles.
ROS overproduction leads to cellular oxidative stress.
This may lead to an irrecoverable imbalance of redox (oxidation-reduction reaction) function that deregulates redox homeostasis, which itself could lead to several diseases including neurodegenerative disease, cardiovascular disease, and cancers.
In this study, we focus on the redox effects related to vascular systems in mammals.
To support research in this domain, we developed an online knowledge base, DES-RedoxVasc, which enables exploration of information contained in the biomedical scientific literature.
The DES-RedoxVasc system analyzed 233399 documents consisting of PubMed abstracts and PubMed Central full-text articles related to different aspects of redox biology in vascular systems.
It allows researchers to explore enriched concepts from 28 curated thematic dictionaries, as well as literature-derived potential associations of pairs of such enriched concepts, where associations themselves are statistically enriched.
For example, the system allows exploration of associations of pathways, diseases, mutations, genes/proteins, miRNAs, long ncRNAs, toxins, drugs, biological processes, molecular functions, etc.
that allow for insights about different aspects of redox effects and control of processes related to the vascular system.
Moreover, we deliver case studies about some existing or possibly novel knowledge regarding redox of vascular biology demonstrating the usefulness of DES-RedoxVasc.
DES-RedoxVasc is the first compiled knowledge base using text mining for the exploration of this topic.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Essack, Magbubah& Salhi, Adil& Stanimirovic, Julijana& Tifratene, Faroug& Bin Raies, Arwa& Hungler, Arnaud…[et al.]. 2019. Literature-Based Enrichment Insights into Redox Control of Vascular Biology. Oxidative Medicine and Cellular Longevity،Vol. 2019, no. 2019, pp.1-16.
https://search.emarefa.net/detail/BIM-1202372
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Essack, Magbubah…[et al.]. Literature-Based Enrichment Insights into Redox Control of Vascular Biology. Oxidative Medicine and Cellular Longevity No. 2019 (2019), pp.1-16.
https://search.emarefa.net/detail/BIM-1202372
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Essack, Magbubah& Salhi, Adil& Stanimirovic, Julijana& Tifratene, Faroug& Bin Raies, Arwa& Hungler, Arnaud…[et al.]. Literature-Based Enrichment Insights into Redox Control of Vascular Biology. Oxidative Medicine and Cellular Longevity. 2019. Vol. 2019, no. 2019, pp.1-16.
https://search.emarefa.net/detail/BIM-1202372
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1202372
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر